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Table 5 Notable mutations in MHR and out of MHR of OBIs

From: Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China

Region Mutation Frequency (%)
OBIB (Genotype B)
 Out of MHR S31 N 3/23 (13%)
Q101Ra 3/23 (13%)
M103I 2/23 (8.7%)
S167 La 3/23 (13%)
V168A 8/23 (34.8%)
R169Ha 2/23 (8.7%)
S174 Na 5/23 (21.7%)
L175Sa 3/23 (13%)
V177Aa 5/23 (21.7%)
 MHR K122R 4/23 (17.4%)
Q129Rab/L/Hb (3 + 1 + 1)/23 (21.7%)
P142L 2/23 (8.7%)
D144Aab/Eb (1 + 1)/23 (8.7%)
G145Aab/Rab (4 + 1)/23 (21.7%)
S154 L/P (3 + 1)/23 (17.4%)
A159V/G (3 + 1)/23 (17.4%)
K160 N/R (2 + 1)/23 (13%)
E164G/A (3 + 1)/23 (17.4%)
Stop codon 2/23 (8.7%)
OBIC (Genotype C)
 Out of MHR Q30K 4/23 (17.4%)
S34 L 2/23 (8.7%)
T47Kb/V/A (3 + 3 + 2)/23 (34.8%)
P49H/L (5 + 1)/23 (26.1%)
S55F 3/23 (13%)
I68T 4/23 (17.4%)
F79H 3/23 (13%)
Q101K/Ra/H/ (3 + 1 + 1)/23 (21.7%)
V168A 4/23 (17.4%)
F170S 2/23 (8.7%)
S174 N 5/23 (21.7%)
L175S 5/23 (21.7%)
V177A 5/23 (21.7%)
Stop codon 1/23 (4.3%)
MHR P111T/S (1 + 1)/23 (8.7%)
T115 Na/I (2 + 1)/23 (13%)
T116A/P/Nab (2 + 1 + 1)/23 (17.4%)
S117G/R (1 + 1)/23 (8.7%)
T118K/R/M (4 + 2 + 1)/23 (30.4%)
K122R 3/23 (13%)
Q129Rab/Pa (2 + 1)/23 (13%)
S136F 3/23 (13%)
S143 La 3/23 (13%)
G145Rab/Aab/K/E (2 + 2 + 1 + 1)/23 (26.1%)
I150T 2/23 (8.7%)
R160K/N (7 + 3)/23 (43.5%)
E164D/V/G (2 + 1 + 1)/23 (17.4%)
  1. aOBI related mutations [14]. bvaccination related mutations [14,15,16,17,18,19,20]