Table 4 Comparison of treatment outcomes between specific drug-containing regimens by drug-resistance pattern (MDR- VS- pre-XDR TB)
| Â | MDR-TB | Pre-XDR TB | p-value | |
|---|---|---|---|---|
Clofazimine-containing regimens | n = 8 | n = 17 |  | |
Treatment outcome, n (%) | Cured | 5 (62.5) | 7 (41.2) | 0.41 |
Treatment completed | 2 (25.0) | 6 (35.3) | 1.0 | |
Died | 1 (12.5) | 3 (17.7) | 1.0 | |
Default | – | 1 (5.9) | 1.0 | |
Transferred out | – | – | – | |
Treatment success | 7 (87.5) | 13 (76.5) | 1.0 | |
Linezolid-containing regimens | n = 23 | n = 23 |  | |
Treatment outcome, n (%) | Cured | 17 (73.9) | 12 (52.2) | 0.22 |
Treatment completed | 3 (13.0) | 8 (34.8) | 0.17 | |
Died | 1 (4.4) | 3 (13.0) | 0.61 | |
Default | 1 (4.4) | – | 1.0 | |
Transferred out | 1 (4.4) | – | 1.0 | |
Treatment success | 20 (87.0) | 20 (87.0) | 1.0 | |
Meropenem-containing regimens | n = 22 | n = 23 |  | |
Treatment outcome, n (%) | Cured | 20 (90.9) | 12 (52.2) | 0.007 |
Treatment completed | 0 (0.0) | 8 (34.8) | 0.004 | |
Died | 2 (9.1) | 3 (13.0) | 1.0 | |
Default | – | – |  | |
Transferred out | – | – |  | |
Treatment success | 20 (90.9) | 20 (87.0) | 1.0 | |
Fluoroquinolones-containing regimens | n = 88 | n = 31 |  | |
Treatment outcome, n (%) | Cured | 39 (44.3) | 13 (41.9) | 0.82 |
Treatment completed | 33 (37.5) | 11 (35.5) | 0.84 | |
Died | 3 (3.4) | 3 (9.7) | 0.18 | |
Default | 9 (10.2) | 1 (3.2) | 0.45 | |
Transferred out | 4 (4.6) | 3 (9.7) | 0.38 | |
Treatment success | 72 (81.8) | 24 (77.4) | 0.59 | |
Amikacin-containing regimens | n = 43 | n = 22 |  | |
Treatment outcome, n (%) | Cured | 28 (65.1) | 8 (36.4) | 0.03 |
Treatment completed | 11 (25.6) | 10 (45.5) | 0.11 | |
Died | 2 (4.7) | 2 (9.1) | 0.60 | |
Default | 1 (2.3) | – | 1.0 | |
Transferred out | 1 (2.3) | 2 (9.1) | 0.26 | |
Treatment success | 39 (90.7) | 18 (81.8) | 0.43 | |