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Table 4 Aetiology by region (Southeast Asia and South Asia)

From: Diversity of infectious aetiologies of acute undifferentiated febrile illnesses in south and Southeast Asia: a systematic review

Organism

SEA (n; %)

South Asia (n; %)

Total (n; %)

Viral aetiologies

7828 (33.0)

7060 (12.4)

14,888 (18.5)

Dengue

2690 (11.4)

6821 (12.0)

9511 (11.8)

JE***

309 (1.3)

0 (0.0)

309 (0.4)

Influenza**

2511 (10.6)

3 (0.0)

2514 (3.1)

HINI

514 (2.2)

5 (0.0)

519 (0.6)

Chikungunya

256 (1.1)

199 (0.3)

455 (0.6)

Hepatitis A

62 (0.3)

11 (0.0)

73 (0.1)

Hepatitis B

267 (1.1)

5 (0.0)

272 (0.3)

Hepatitis E

1038 (4.4)

2 (0.0)

1040 (1.3)

Flavi virus

65 (0.3)

0 (0.0)

65 (0.1)

Para influenza 1

10 (0.0)

0 (0.0)

10 (0.0)

Para influenza 3

28 (0.1)

0 (0.0)

28 (0.0)

Hanta virus

71 (0.3)

2 (0.0)

73 (0.1)

HIV

7 (0.0)

12 (0.0)

19 (0.0)

Bacterial aetiologies

4873 (20.6)

5512 (9.7)

10,385 (12.9)

Leptospirosis

2861 (12.1)

688 (1.2)

3549 (4.4)

Typhoid

809 (3.4)

2449 (4.3)

3258 (4.0)

Paratyphoid

0 (0.0)

57 (0.1)

57 (0.1)

Rickettsial diseases

1009 (4.3)

2234 (3.9)

3243 (4.0)

Scrub typhus

764 (3.2)

2095 (3.7)

2859 (3.5)

Murine typhus

146 (0.6)

126 (0.2)

272 (0.3)

Spotted fever

99 (0.4)

13 (0.0)

112 (0.1)

Q fever

7 (0.0)

0 (0.0)

7 (0.0)

E coli

49 (0.2)

9 (0.0)

58 (0.1)

Burkholderia pseudomallei

23 (0.1)

0 (0.0)

23 (0.0)

Tuberculosis

21 (0.1)

22 (0.0)

43 (0.1)

Klebsiella pneumoniae

3 (0.0)

1 (0.0)

4 (0.0)

Haemophilus influenza

9 (0.0)

0 (0.0)

9 (0.0)

Staph aureus

49 (0.2)

0 (0.0)

49 (0.1)

Strep pneumoniae

24 (0.1)

51 (0.1)

75 (0.1)

Strep Gr A

2 (0.0)

0 (0.0)

2 (0.0)

Strep Gr C

1 (0.0)

0 (0.0)

1 (0.0)

Neisseria meningitides

6 (0.0)

1 (0.0)

7 (0.0)

Protozoa

559 (2.4)

1722 (3.0)

2281 (2.8)

Malaria

559 (2.4)

1722 (3.0)

2281 (2.8)

Fungal aetiologies

3 (0.0)

0 (0.0)

3 (0.0)

Yeast non Cryptococci

2 (0.0)

0 (0.0)

2 (0.0)

Cryptococcus neoformans

1 (0.0)

0 (0.0)

1 (0.0)

Co infections

815 (3.4)

196 (0.3)

1011 (1.3)

Co infection*

592 (2.5)

178 (0.3)

770 (1.0)

Co infection†

217 (0.9)

18 (0.0)

235 (0.3)

Co infection‡

6 (0.0)

0 (0.0)

6 (0.0)

Unknown

9621 (40.6)

42,389 (74.5)

52,010 (64.5)

Deaths

114 (30.2)

264 (69.8)

378 (100.0)

  1. South Asian countries included: India, Bhutan, Bangladesh, Sri Lanka, and Nepal
  2. Southeast Asian (SEA) countries included: Thailand, Indonesia, Malaysia, Laos, Philippines, Cambodia and Vietnam ***JE- Japanese B encephalitis;
  3. **influenza other than H1N1; *co-infection with two organisms; †co-infection with three organisms; ‡co-infection with more than three organisms
  4. The bold face shows the cumulative number of the stratified groups