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Table 4 Age- and gender-adjusted-risk factors for death of patients during the 2011–2017 and 2017–2018 influenza seasons

From: Clinical characteristics and outcomes during a severe influenza season in China during 2017–2018

Risk factors

2017–2018

2011–2017

n (%)

Adjusted OR(95%CI)

n (%)

Adjusted OR(95%CI)

Cancer and Hematological diseases

83 (28.7)

3.1 (1.2–8.1)

56 (33.1)

0.0 (0.0-)

WBC < 4

70 (24.2)

3.5 (1.2–10.4)

50 (29.6)

2.3 (0.0-)

LDH > 300

108 (42.7)

7.6 (2.3–25.2)

48 (35.6)

1.0 (0.0-)

AKI

19 (6.6)

10.1 (2.9–34.6)

4 (2.4)

0.0 (0.0-)

DIC

20 (6.9)

56.4 (14.5–219.3)

3 (1.8)

1.9 (0.0-)

Secondary bacterial infection

72 (24.9)

4.4 (1.6–12.4)

13 (7.7)

2.8 (0.0-)

ARDS

20 (6.9)

32.2 (8.7–112.2)

2 (1.2)

NA

Respiratory Failure

62 (21.5)

11.7 (4.0–34.2)

10 (5.9)

3.2 (0.0-)

Shock

9 (3.1)

23.7 (4.9–115.2)

1 (0.6)

0.0 (0.0-)

MOF

9 (3.1)

15.5 (3.0–79.5)

0 (0)

NA

Glucocorticoids

134 (46.4)

11.6 (2.6–52.4)

64 (37.9)

1.5 (0.1–25.5)

  1. AKI acute kidney injury, DIC disseminated intravascular coagulation, ARDS acute respiratory distress syndrome, MOF multiple organ failure
  2. WBC, white cell (109/L), LDH lactate dehydrogenase (u/L)
  3. CI confidence interval, OR odds ratio, NA not available