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Table 4 Age- and gender-adjusted-risk factors for death of patients during the 2011–2017 and 2017–2018 influenza seasons

From: Clinical characteristics and outcomes during a severe influenza season in China during 2017–2018

Risk factors2017–20182011–2017
n (%)Adjusted OR(95%CI)n (%)Adjusted OR(95%CI)
Cancer and Hematological diseases83 (28.7)3.1 (1.2–8.1)56 (33.1)0.0 (0.0-)
WBC < 470 (24.2)3.5 (1.2–10.4)50 (29.6)2.3 (0.0-)
LDH > 300108 (42.7)7.6 (2.3–25.2)48 (35.6)1.0 (0.0-)
AKI19 (6.6)10.1 (2.9–34.6)4 (2.4)0.0 (0.0-)
DIC20 (6.9)56.4 (14.5–219.3)3 (1.8)1.9 (0.0-)
Secondary bacterial infection72 (24.9)4.4 (1.6–12.4)13 (7.7)2.8 (0.0-)
ARDS20 (6.9)32.2 (8.7–112.2)2 (1.2)NA
Respiratory Failure62 (21.5)11.7 (4.0–34.2)10 (5.9)3.2 (0.0-)
Shock9 (3.1)23.7 (4.9–115.2)1 (0.6)0.0 (0.0-)
MOF9 (3.1)15.5 (3.0–79.5)0 (0)NA
Glucocorticoids134 (46.4)11.6 (2.6–52.4)64 (37.9)1.5 (0.1–25.5)
  1. AKI acute kidney injury, DIC disseminated intravascular coagulation, ARDS acute respiratory distress syndrome, MOF multiple organ failure
  2. WBC, white cell (109/L), LDH lactate dehydrogenase (u/L)
  3. CI confidence interval, OR odds ratio, NA not available