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Table 4 Results for faecal swab clinical extracts (n = 460). Regarding ‘n/a’ results, only clinical extracts positive by the Carba (beta) assay were subjected to in-house assays and DNA sequencing

From: Evaluation of the SpeeDx Carba (beta) multiplex real-time PCR assay for detection of NDM, KPC, OXA-48-like, IMP-4-like and VIM carbapenemase genes

n Carba (beta) assay Ct values (range; mean) In-house assays Ct values (range; mean) Sequencing result
KPC NDM OXA-48-like IMP-4-like/VIM IC KPC NDM OXA-48-like IMP-4-like VIM 16S rRNA
1 neg neg neg POSITIVE
(25.4)
POSITIVE
(22.6)
n/a n/a n/a POSITIVE
(31.4)
neg POSITIVE
(11.2)
IMP-4
1 neg neg POSITIVE
(27.0)
neg POSITIVE
(23.4)
n/a n/a neg n/a n/a POSITIVE
(15.5)
OXA-181
6 neg neg POSITIVE
(25.1–28.9; 27.1)
neg POSITIVE
(22.3–24.4; 23.0)
n/a n/a neg n/a n/a POSITIVE
(12.4–18.7; 14.2)
n/a
452 neg neg neg neg POSITIVE
(21.4–28.7; 22.8)
n/a n/a n/a n/a n/a n/a n/a
  1. neg negative
  2. n/a not available