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Table 2 Genotyping calls of infection as recrudescent or new infection based on one or more markers. PCR-corrected treatment outcomes based on MSP-2 or all six molecular markers

From: Comparison on simultaneous capillary and venous parasite density and genotyping results from children and adults with uncomplicated malaria: a prospective observational study in Uganda

 

Marker

Capillary-Capillary

Capillary-Venous

Venous-Venous

Venous-Capillary

% Recrudescence (n)

MSP- 2 alone

19% (9)

30% (14)

25%(12)

27% (13)

All 6 markers

5.8% (3)

4% (2)

2% (1)

4% (2)

  1. Genotyping calls based on MSP-2 alone or all six markers, in the four possible compartment combinations on day 0 and day of failure. There is a high degree of variability in genotyping calls between pairs of samples from each compartment using MSP-2 alone, although the variability is reduced with the use of multiple markers