Comparison on simultaneous capillary and venous parasite density and genotyping results from children and adults with uncomplicated malaria: a prospective observational study in Uganda

BMC Infectious Diseases

Table 2 Genotyping calls of infection as recrudescent or new infection based on one or more markers. PCR-corrected treatment outcomes based on MSP-2 or all six molecular markers

	Marker	Capillary-Capillary	Capillary-Venous	Venous-Venous	Venous-Capillary
% Recrudescence (n)	MSP- 2 alone	19% (9)	30% (14)	25%(12)	27% (13)
% Recrudescence (n)	All 6 markers	5.8% (3)	4% (2)	2% (1)	4% (2)

Genotyping calls based on MSP-2 alone or all six markers, in the four possible compartment combinations on day 0 and day of failure. There is a high degree of variability in genotyping calls between pairs of samples from each compartment using MSP-2 alone, although the variability is reduced with the use of multiple markers