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Table 3 Detection of dengue and chikungunya by RDT and ELISA in the 293 subjects for whom sufficient plasma was available

From: Dengue, chikungunya, and scrub typhus are important etiologies of non-malarial febrile illness in Rourkela, Odisha, India

Antigen

Type of test

Manufacturer (no. of patients tested)

Positive cases

% Positivity

Concordance between tests

Dengue NS1 (n = 293)

RDT

J. Mitra (n = 290)

39

13.4

NS1 RDT:

J. Mitra vs. SD Bioline: 100% same results, n = 101

SD Bioline (n = 101)

13

12.9

ELISA

Panbio (n = 288)

41

14.2

J. Mitra RDT vs. Panbio ELISA (NS1):

McNemar test, n = 285, exact p-value 0.688

Dengue IgM (n = 293)

RDT

J. Mitra (n = 290)

16

5.5

IgM RDT:

J. Mitra vs. SD Bioline: McNemar test, N = 101, exact p-value 0.625

SD Bioline (n = 101)

1

1

ELISA

Panbio (n = 288)

35

12.2

J. Mitra RDT vs. Panbio ELISA (NS1):

McNemar test, n = 285, exact p-value 0.688

Dengue IgG (n = 290)

RDT

J. Mitra (n = 290)

8

2.8

IgG RDT:

J. Mitra vs. SD Bioline: 100% same results, n = 101

SD Bioline (n = 101)

2

2

Dengue NS1 or Dengue IgG or Dengue IgM

RDT or ELISA

J. Mitra or SD Bioline or Panbio (n = 293)

74

25.3

Not applicable

chikungunya IgM (n = 293)

RDT

J. Mitra (n = 288)

8

2.8

IgM RDT:

J. Mitra vs. SD Bioline: McNemar test, n = 100, exact p-value 0.250

SD Bioline (n = 102)

0

0

ELISA

Panbio (n = 288)

15

5.2

J. Mitra RDT vs. Panbio IgM ELISA:

McNemar test, n = 283, exact p-value 0.022

RDT or ELISA

J. Mitra or SD Bioline or Panbio (n = 293)

17

5.8

Not applicable