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Table 2 Results of the univariable analysis for factors associated with HIV-1 seroconversion

From: HIV-seroconversion among HIV-1 serodiscordant married couples in Tanzania: a cohort study

Variable

Person-time (in years)

Number of events

Hazard ratio

[95%CI]

p-value

Variables concerning the baseline individual

 Sex

Male

221.50

13

0.11[0.015–0.87]

0.036

Female

149.43

1

 Education

Never attended school

294.91

14

0[0]a

0.992

Ever attended school

71.01

0

 ART intake

No

318.72

14

0[0]a

0.992

Yes

50.06

0

 Ln(CAA)d

–

–

–

1.18[0.93–1.49]

0.177

 STI symptoms

No

291.31

11

1.03[0.29–3.68]

0.969

Yes

77.46

3

 Schistosome CAA positivity

Negative

167.80

5

1.35[0.43–4.24]

0.611

Positive

172.27

7

Variables concerning the serodiscordant spouse

 Sex

Male

149.43

1

8.77[1.15–67.04]

0.036

Female

221.50

13

 Education

Never attended school

234.99

11

0.48[0.13–1.72]

0.258

Ever attended school

135.94

3

 Other risks for HIVbd

No

297.77

14

0[0]a

0.994

Yes

71.00

0

 Risky sex behaviorc,d

No

66.43

4

0[0]a

0.994

Yes

19.15

0

 Ln(CAA) d

–

–

–

1.11[0.85–1.44]

0.453

 Number of extramarital partnersd

None

303.95

14

0[0]a

0.994

One or more

66.97

0

 STI Symptomsd

No

285.8

12

0.57[0.13–2.57]

0.468

Yes

82.94

2

 Schistosome CAA positivity

Negative

152.33

6

1.03[0.36–2.98]

0.953

Positive

196.75

8

Variables concerning the couple

 Age difference between the baseline individual and his/her spouse in years

–

–

–

1.00[0.9991–1.001]

0.734

 Sex frequencyd

Less than once a month

37.22

1

  

Between once a month and once a week

134.64

6

1.66[0.20–13.78]

0.639

More than once a week

166.50

5

1.12[0.13–9.57]

0.919

  1. aNo convergence of the model due to presence of zeros. No conclusion on the association between the variable and seroconversion can be made due to short person-time available. ART was still included in the final model stepwise analysis
  2. bOther risks for HIV include incisions and transfusions
  3. cRisky sex behaviors include having sex with women at bars or with traveling men
  4. dSurvey-dependent variables