Cytokines | NHC (n = 52) | CHB (n = 78) | HBV-related cirrhosis (n = 73) | P-values |
---|---|---|---|---|
CCL5 | 9335.99 (526.34–18,975.78) | 11,729.47 (564.78–15,610.99) | 4375.79 (890.92–14,658.46) ### *** | < 0.001 |
MIP-1β | 80.45 (29.08–145.58) | 75.77 (26.00–225.33) | 49.3 (26.56–72.53) # * | < 0.01 |
MIP-1α | 0.31 (0.18–2.15) | 0.34 (0.18–3.21) | 0.29 (0.18–0.49) | ns |
IL-2 | 11.91 (4.32–198.55) | 10.86 (5.09–112.64) | 12.26 (6.62–271.74) | ns |
IL-5 | 2.87 (1.15–8.34) | 3.50 (1.50–7.02) | 3.18 (1.24–6.08) | ns |
IL-4 | 1.11 (0.81–3.88) | 1.34 (0.81–5.65) | 1.25 (0.89–1.84) | ns |
IL-6 | 9.02 (4.08–112.55) | 8.80 (4.58–88.19) | 9.23 (4.28–162.78) | ns |
IL-7 | 1.35 (0.91–8.33) | 1.40 (0.98–9.04) | 1.29 (0.94–3.25) | ns |
IL-8 | 54.47 (8.54–974.35) | 47.13 (9.60–3658.40) | 27.20 (9.89–254.21) | ns |
IL-10 | 4.94 (2.15–98.49) | 4.80 (2.30–60.45) | 4.10 (2.20–330.67) | ns |
IL-1β | 0.16 (0.09–1.11) | 0.15 (0.09–1.69) | 0.14 (0.09–0.29) | ns |
IL-12 | 4.18 (2.85–158.63) | 3.99 (2.55–272.81) | 5.63 (2.79–391.44) | ns |
IL-13 | 1.18 (0.89–2.44) | 1.09 (0.83–2.64) | 1.26 (0.91–2.38) | ns |
IL-17 | 38.55 (20.63–99.65) | 40.92 (20.99–184.84) | 37.34 (21.97–93.25) | ns |
G-CSF | 18.88 (13.70–65.23) | 17.80 (13.70–71.55) | 20.78 (13.70–40.07) | ns |
GM-CSF | 45.26 (15.26–19.48) | 46.79 (19.00–280.83) | 54.43 (14.54–150.88) | ns |
IFN-γ | 35.12 (20.99–53.54) | 33.83 (20.81–58.76) | 30.63 (20.81–55.70) | ns |
MCP-1 | 20.07 (9.02–189.64) | 18.60 (9.02–203.89) | 13.97 (9.02–30.28) | ns |
TNF-α | 8.18 (6.99–84.57) | 8.11 (6.25–73.31) | 8.16 (6.87–96.67) | ns |