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Table 3 Comparison of the drug resistance of major gram-negative bacteria to commonly used antibacterial agents between nosocomial and community-acquired SBP

From: Causative agents and outcome of spontaneous bacterial peritonitis in cirrhotic patients: community-acquired versus nosocomial infections

Antibiotics Escherichia coli (n = 81) Klebsiella pneumoniae (n = 40)
Nosocomial
(n = 32)
Community-acquired (n = 49) p value Nosocomial
(n = 14)
Community-acquired (n = 26) p value
ESBL 25 (78.1) 15 (30.6) 0.000 4 (28.6) 2 (7.7) 0.194
Ampicillin 29 (90.6) 43 (87.8) 0.968 14 (100) 24 (92.3) 0.533
Piperacillin 28 (87.5) 37 (75.5) 0.299 6 (42.9) 3 (11.5) 0.062
Amoxicillin-clavulanic acid 12 (37.5) 10 (20.4) 0.091 3 (21.4) 1 (3.8) 0.224
Piperacillin/tazobactam 4 (12.5) 0 0.022 2 (14.3) 0 0.117
Cefazolin 26 (81.2) 13 (26.5) 0.000 4 (28.6) 4 (15.4) 0.562
Ceftazidime 25 (78.1) 13 (26.5) 0.000 4 (28.6) 2 (7.7) 0.194
Cefotaxime 27 (84.3) 15 (30.6) 0.000 4 (28.6) 2 (7.7) 0.194
Cefepime 23 (71.9) 11 (22.4) 0.000 4 (28.6) 0 0.011
Aztreonam 18 (56.3) 10 (20.4) 0.001 2 (14.3) 1 (3.8) 0.571
Imipenem 2 (6.3) 0 0.153 2 (14.3) 0 0.117
Meropenem 1 (3.1) 0 0.395 1 (7.1) 0 0.350
Amikacin 2 (6.3) 0 0.153 1 (7.1) 0 0.350
Levofloxacin 23 (71.9) 21 (42.9) 0.01 3 (21.4) 1 (3.8) 0.224
SMZ 21 (65.6) 30 (61.2) 0.688 3 (21.4) 4 (15.4) 0.965
Gentamicin 17 (53.1) 25 (51.0) 0.853 2 (14.3) 2 (7.7) 0.912
Tetracycline 25 (78.1) 39 (79.6) 0.874 4 (28.6) 4 (15.4) 0.562