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Table 8 MIC distribution of Eravacycline and relevant antibiotics against H. influenza of different resistance characteristics

From: In vitro activities of Eravacycline against 336 isolates collected from 2012 to 2016 from 11 teaching hospitals in China

Antibiotics

β-lactamases negative, n = 10

β-lactamases positive, n = 10

MIC50

MIC90

Range

MIC50

MIC90

Range

Eravacycline

0.064

0.125

0.064–0.125

0.064

0.125

0.032–0.125

Tigecycline

0.25

0.5

0.125–0.5

0.125

0.25

0.064–0.5

Ampicillin

0.125

0.5

0.125–1

16

64

0.064–64

Amoxicillin/Clavulanic acid

0.125

0.5

0.125–0.5

1

1

0.5–1

Penicillin

16

32

0.032–32

16

32

1–64

Cefaclor

2

8

0.5–8

4

16

1–32

Cefuroxime

1

2

0.25–4

1

4

0.25–16

Azithromycin

1

4

0.064–4

2

64

0.25–64

Clarithromycin

4

16

0.5–16

4

64

1–64

Levofloxacin

0.032

1

0.016–1

0.032

0.125

0.016–0.5

Moxifloxacin

0.032

1

0.016–1

0.032

0.25

0.016–0.5

Trimethoprim/Sulfamethoxazole

16

32

0.032–32

16

32

1–64

Tetracycline

1

4

0.064–4

2

64

0.25–64

Chloramphenicol

0.5

1

0.25–1

1

8

0.5–8