In vitro activities of Eravacycline against 336 isolates collected from 2012 to 2016 from 11 teaching hospitals in China

Table 6 MIC distribution of Eravacycline and relevant antibiotics against Enterococci. spp of different resistance characteristics

Antibiotics	E.faecalis, n = 10			E.faecium, n = 8			VRE^a, n = 3
Antibiotics	MIC₅₀	MIC₉₀	Range	MIC₅₀	MIC₉₀	Range	MIC₅₀	MIC₉₀	Range
Eravacycline	0.032	0.032	0.016–0.125	0.016	0.032	0.008–0.064	0.016	0.032	0.008–0.032
Tigecycline	0.064	0.064	0.064–0.125	0.064	0.064	0.016–0.125	0.125	0.25	0.125–0.25
Ampicillin	1	8	1–8	64	64	4–64	64	64	64–64
Vancomycin	1	2	0.5–2	0.5	1	0.25–1	128	128	128–128
Teicoplanin	0.125	0.25	0.032–0.25	0.25	0.25	0.064–0.25	32	64	32–64
Erythromycin	1	256	0.25–256	256	256	0.016–256	0.125	256	0.125–256
Minocycline	16	16	0.064–16	0.032	16	0.032–16	0.064	16	0.064–16
Ciprofloxacin	2	32	0.5–64	64	64	4–64	64	64	64–64
Levofloxacin	2	64	1–64	64	128	1–128	64	64	64–64
Linezolid	1	2	1–2	1	1	0.5–1	1	1	1–1

^a VRE referred to vancomycin-resistant Enterococci. All of the 3 VRE strains in this study were E.faecium

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