From: Nontuberculous mycobacterial pulmonary disease diagnosed by two methods: a prospective cohort study
Variables | Total patients N = 347 | Sputum group n = 279 | Bronchoscopy group n = 68 | P-value |
---|---|---|---|---|
Sex, female | 215 (62.0) | 176 (63.1) | 39 (57.4) | 0.383 |
Age, years | 66 (59, 74) | 67 (59, 74) | 66 (58, 74) | 0.509 |
Smoking history | 0.985 | |||
 Never smoker | 258 (74.4) | 208 (74.6) | 50 (73.5) |  |
 Former smoker | 79 (22.8) | 63 (22.6) | 16 (23.5) |  |
 Current smoker | 10 (2.9) | 8 (2.9) | 2 (2.9) |  |
Pack-years for smokers | 20 (10, 30) | 22.5 (15, 33.8) | 13.8 (5, 20) | 0.046 |
History of tuberculosis | 131 (37.8) | 116 (41.6) | 15 (22.1) | 0.008 |
Smear positivity of specimen on diagnosis | 62 (17.9) | 47 (16.9) | 15 (22.1) | 0.314 |
Underlying disease | ||||
 COPD | 32 (9.2) | 28 (10.0) | 4 (5.9) | 0.288 |
 GERD | 27 (7.8) | 23 (8.3) | 4 (5.9) | 0.583 |
 Cancer | 22 (6.3) | 18 (6.5) | 4 (5.9) | 0.863 |
 Diabetes mellitus | 22 (6.3) | 16 (5.7) | 6 (8.8) | 0.349 |
Occupational status | 0.583 | |||
 Office work | 53 (15.3) | 42 (15.1) | 11 (16.2) |  |
 Housewife | 53 (15.3) | 41 (14.7) | 12 (17.7) |  |
 Professional practitioner | 41 (11.8) | 33 (11.8) | 8 (11.8) |  |
 Self-employment | 38 (11.0) | 32 (11.5) | 6 (8.8) |  |
 Unemployed | 21 (6.1) | 18 (6.5) | 3 (4.4) |  |
 Construction worker | 14 (4.0) | 13 (4.7) | 1 (1.5) |  |
 Service industry | 14 (4.0) | 12 (4.3) | 2 (2.9) |  |
Radiographic subtype | 0.288 | |||
 Nodular bronchiectatic form | 315 (90.8) | 251 (90.0) | 64 (94.1) |  |
 Upper lobe cavitary form | 32 (9.2) | 28 (10.0) | 4 (5.9) |  |
NTM species | 0.184 | |||
 Mycobacterium avium | 129 (37.2) | 97 (34.8) | 32 (47.1) |  |
 Mycobacterium intracellulare | 110 (31.7) | 91 (32.6) | 19 (27.9) |  |
 Other MAC | 4 (1.2) | 4 (1.4) | 0 (0.0) |  |
 Mycobacterium abscessus subsp. abscessus | 32 (9.2) | 25 (9.0) | 7 (10.3) |  |
 Mycobacterium abscessus subsp. massiliense | 31 (8.9) | 28 (10.0) | 3 (4.4) |  |
 Mycobacterium kansasii | 7 (2.0) | 6 (2.2) | 1 (1.5) |  |
 Mycobacterium fortuitum | 3 (0.9) | 3 (1.1) | 0 (0.0) |  |
 Others | 13 (3.7) | 10 (3.6) | 3 (4.4) |  |
 Mixed infectiona | 12 (3.5) | 12 (4.3) | 0 (0.0) |  |
 Unknownb | 6 (1.7) | 3 (1.1) | 3 (4.4) |  |