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Table 1 Baseline characteristics of 347 patients diagnosed with nontuberculous mycobacterial pulmonary disease using different diagnostic methods

From: Nontuberculous mycobacterial pulmonary disease diagnosed by two methods: a prospective cohort study

Variables Total patients N = 347 Sputum group n = 279 Bronchoscopy group n = 68 P-value
Sex, female 215 (62.0) 176 (63.1) 39 (57.4) 0.383
Age, years 66 (59, 74) 67 (59, 74) 66 (58, 74) 0.509
Smoking history 0.985
 Never smoker 258 (74.4) 208 (74.6) 50 (73.5)  
 Former smoker 79 (22.8) 63 (22.6) 16 (23.5)  
 Current smoker 10 (2.9) 8 (2.9) 2 (2.9)  
Pack-years for smokers 20 (10, 30) 22.5 (15, 33.8) 13.8 (5, 20) 0.046
History of tuberculosis 131 (37.8) 116 (41.6) 15 (22.1) 0.008
Smear positivity of specimen on diagnosis 62 (17.9) 47 (16.9) 15 (22.1) 0.314
Underlying disease
 COPD 32 (9.2) 28 (10.0) 4 (5.9) 0.288
 GERD 27 (7.8) 23 (8.3) 4 (5.9) 0.583
 Cancer 22 (6.3) 18 (6.5) 4 (5.9) 0.863
 Diabetes mellitus 22 (6.3) 16 (5.7) 6 (8.8) 0.349
Occupational status 0.583
 Office work 53 (15.3) 42 (15.1) 11 (16.2)  
 Housewife 53 (15.3) 41 (14.7) 12 (17.7)  
 Professional practitioner 41 (11.8) 33 (11.8) 8 (11.8)  
 Self-employment 38 (11.0) 32 (11.5) 6 (8.8)  
 Unemployed 21 (6.1) 18 (6.5) 3 (4.4)  
 Construction worker 14 (4.0) 13 (4.7) 1 (1.5)  
 Service industry 14 (4.0) 12 (4.3) 2 (2.9)  
Radiographic subtype 0.288
 Nodular bronchiectatic form 315 (90.8) 251 (90.0) 64 (94.1)  
 Upper lobe cavitary form 32 (9.2) 28 (10.0) 4 (5.9)  
NTM species 0.184
Mycobacterium avium 129 (37.2) 97 (34.8) 32 (47.1)  
Mycobacterium intracellulare 110 (31.7) 91 (32.6) 19 (27.9)  
Other MAC 4 (1.2) 4 (1.4) 0 (0.0)  
Mycobacterium abscessus subsp. abscessus 32 (9.2) 25 (9.0) 7 (10.3)  
Mycobacterium abscessus subsp. massiliense 31 (8.9) 28 (10.0) 3 (4.4)  
Mycobacterium kansasii 7 (2.0) 6 (2.2) 1 (1.5)  
Mycobacterium fortuitum 3 (0.9) 3 (1.1) 0 (0.0)  
 Others 13 (3.7) 10 (3.6) 3 (4.4)  
 Mixed infectiona 12 (3.5) 12 (4.3) 0 (0.0)  
 Unknownb 6 (1.7) 3 (1.1) 3 (4.4)  
  1. Values are presented as number (percentage) or median (interquartile range)
  2. Abbreviations: COPD chronic obstructive pulmonary disease, GERD gastroesophageal reflux disease, NTM nontuberculous mycobacteria, MAC Mycobacterium avium complex
  3. a More than two NTM species isolated at least twice each during the follow-up period until the start of treatment. bThe results of species identification for NTM are missing