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Table 1 Baseline characteristics of 347 patients diagnosed with nontuberculous mycobacterial pulmonary disease using different diagnostic methods

From: Nontuberculous mycobacterial pulmonary disease diagnosed by two methods: a prospective cohort study

Variables

Total patients N = 347

Sputum group n = 279

Bronchoscopy group n = 68

P-value

Sex, female

215 (62.0)

176 (63.1)

39 (57.4)

0.383

Age, years

66 (59, 74)

67 (59, 74)

66 (58, 74)

0.509

Smoking history

0.985

 Never smoker

258 (74.4)

208 (74.6)

50 (73.5)

 

 Former smoker

79 (22.8)

63 (22.6)

16 (23.5)

 

 Current smoker

10 (2.9)

8 (2.9)

2 (2.9)

 

Pack-years for smokers

20 (10, 30)

22.5 (15, 33.8)

13.8 (5, 20)

0.046

History of tuberculosis

131 (37.8)

116 (41.6)

15 (22.1)

0.008

Smear positivity of specimen on diagnosis

62 (17.9)

47 (16.9)

15 (22.1)

0.314

Underlying disease

 COPD

32 (9.2)

28 (10.0)

4 (5.9)

0.288

 GERD

27 (7.8)

23 (8.3)

4 (5.9)

0.583

 Cancer

22 (6.3)

18 (6.5)

4 (5.9)

0.863

 Diabetes mellitus

22 (6.3)

16 (5.7)

6 (8.8)

0.349

Occupational status

0.583

 Office work

53 (15.3)

42 (15.1)

11 (16.2)

 

 Housewife

53 (15.3)

41 (14.7)

12 (17.7)

 

 Professional practitioner

41 (11.8)

33 (11.8)

8 (11.8)

 

 Self-employment

38 (11.0)

32 (11.5)

6 (8.8)

 

 Unemployed

21 (6.1)

18 (6.5)

3 (4.4)

 

 Construction worker

14 (4.0)

13 (4.7)

1 (1.5)

 

 Service industry

14 (4.0)

12 (4.3)

2 (2.9)

 

Radiographic subtype

0.288

 Nodular bronchiectatic form

315 (90.8)

251 (90.0)

64 (94.1)

 

 Upper lobe cavitary form

32 (9.2)

28 (10.0)

4 (5.9)

 

NTM species

0.184

 Mycobacterium avium

129 (37.2)

97 (34.8)

32 (47.1)

 

 Mycobacterium intracellulare

110 (31.7)

91 (32.6)

19 (27.9)

 

 Other MAC

4 (1.2)

4 (1.4)

0 (0.0)

 

 Mycobacterium abscessus subsp. abscessus

32 (9.2)

25 (9.0)

7 (10.3)

 

 Mycobacterium abscessus subsp. massiliense

31 (8.9)

28 (10.0)

3 (4.4)

 

 Mycobacterium kansasii

7 (2.0)

6 (2.2)

1 (1.5)

 

 Mycobacterium fortuitum

3 (0.9)

3 (1.1)

0 (0.0)

 

 Others

13 (3.7)

10 (3.6)

3 (4.4)

 

 Mixed infectiona

12 (3.5)

12 (4.3)

0 (0.0)

 

 Unknownb

6 (1.7)

3 (1.1)

3 (4.4)

 
  1. Values are presented as number (percentage) or median (interquartile range)
  2. Abbreviations: COPD chronic obstructive pulmonary disease, GERD gastroesophageal reflux disease, NTM nontuberculous mycobacteria, MAC Mycobacterium avium complex
  3. a More than two NTM species isolated at least twice each during the follow-up period until the start of treatment. bThe results of species identification for NTM are missing