Table 1 Baseline demographic and clinical characteristics of patients before and after propensity score matched analysis
Before matching | Propensity score matched | |||||
|---|---|---|---|---|---|---|
Characteristics | DAP (N = 28) | VAN (N = 44) | p | DAP (N = 16) | VAN (N = 16) | p |
Male sex, n (%) | 17 (61) | 34 (77) | .215 | 10 (63) | 11 (69) | 1 |
Age, y | 60.0 [52.3–70.5] | 63.0 [54.0–75.3] | .206 | 56.0 [49.5–69.3] | 65.0 [49.0–78.0] | .086 |
Weight, kg | 74.0 [61.5–80.5] | 72.0 [64.5–80.0] | .827 | 71.5 [61.5–79.3] | 75.0 [63.0–85.3] | .383 |
Height, cm | 170 [163–173] | 167 [165–175] | .821 | 170 [165–174] | 167 [161–169] | .179 |
History of CRcl < 50 ml/min, n (%) | 8 (28.6) | 5 (11.4) | .125 | 2 (12.5) | 2 (12.5) | 1 |
History of diabetes mellitus, n (%) | 10 (35.7) | 11 (25.0) | .478 | 4 (25.0) | 6 (37.5) | .704 |
History of hypertension | 10 (35.7) | 23 (52.3) | .258 | 5 (31.3) | 8 (50.0) | .473 |
Heart failure (EF < 50%), n (%) | 18 (64.3) | 16 (36.4) | .038 | 12 (75.0) | 4 (25.0) | .012 |
CPB during surgery, n (%) | 9 (32.1) | 25 (56.8) | .071 | 7 (43.8) | 7 (43.8) | 1 |
VAD, n (%) | 7 (25) | 7 (15.9) | .519 | 5 (31.3) | 1 (6.3) | .172 |
Circulatory shock at baseline, n (%) | 8 (28.6) | 21 (47.8) | .171 | 4 (25.0) | 9 (56.3) | .149 |
Others nephrotoxic agentsa, n (%) | 18 (64.3) | 29 (65.9) | .910 | 9 (56.3) | 11 (68.7) | .716 |
SAPS II score at ICU admission | 44.5 [35.3–57.8] | 45.5 [34.0–57.8] | .894 | 51.0 [38.5–61.5] | 48.0 [35.0–57.0] | .984 |
SOFA score at baseline | 5 [2–9] | 6 [3–9] | .388 | 4 [2–7] | 6 [3–8] | .281 |
Serum creatinine at baseline, μmol/l | 110 [77–142] | 99 [72–134] | .699 | 87 [64–126] | 94 [69–124] | .440 |
AKI at baseline, n (%) | 7 (25.0) | 13 (29.5) | .881 | 2 (12.5) | 6 (37.5) | .220 |
Previous antibiotic treatment, n (%) | 19 (67.8) | 24 (54.5) | .381 | 8 (50) | 8 (50) | 1 |
GPC bacteraemia, n (%) | 16 (57.1) | 12 (27.3) | .022 | 11 (68.8) | 10 (62.5) | .710 |