Table 3 Patient characteristics

Age, years, median (range)

57.9 (18.3–94.1)

54.6 (18.3–79.5)

55.9 (21.0–87.6)

62.2 (29.4–94.2)

0.002

Female sex

80 (41.6)

32 (40)

25 (44.6)

23 (41)

0.86

Charlson comorbidity index, median (range)

2 (0–8)

1 (0–8)

2 (0–6)

2 (0–7)

0.15

 Myocardial infarction

10 (5.2)

3 (3.7)

3 (5.4)

4 (7.1)

0.71

 Congestive cardiac insufficiency

16 (8.3)

7 (8.7)

1 (1.8)

8 (14.2)

0.13

 Peripheral vascular disease

12 (6.2)

2 (2.5)

1 (1.8)

9 (16)

0.006

 Chronic pulmonary disease

78 (40.6)

64 (80)

5 (8.9)

9 (16)

< 0.001

 Conjuctive tissue disease

0

0

0

0

n.a

 Diabetes without complications

27 (14)

11 (13.7)

2 (3.6)

14 (25)

0.017

 Peptic ulcer disease

2 (1)

1 (1.2)

0

1 (1.8)

0.50

 Chronic disease of the liver or cirrhosis

3 (1.6)

0

0

3 (5.4)

0.07

 Hemiplegia

2 (1)

1 (1.2)

0

1 (1.8)

0.67

 Moderate or severe kidney disease

22 (11.5)

11 (13.7)

4 (7.1)

7 (12.5)

0.47

 Diabetes with chronic complications

6 (3.1)

1 (1.2)

0

5 (8.9)

0.035

 Solid organ malignancy

12 (6.2)

4 (5)

1 (1.8)

7 (12.5)

0.054

 Leukemia

20 (10.4)

1 (1.2)

19 (33.9)

0

< 0.001

 Lymphoma

7 (3.6)

1 (1.2)

5 (8.9)

1 (1.8)

0.10

 Moderate or severe liver disease

16 (8.3)

7 (8.7)

4 (7.1)

5 (8.9)

0.81

 Malignant tumor, metastasis

5 (2.6)

4 (5)

0

1 (1.8)

0.30

 AIDS

2 (1)

0

1 (1.8)

1 (1.8)

0.49

 Dementia

1 (0.5)

1 (1.2)

0

0

0.59