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Table 2 Correlates of vaccine efficacy final logistic regression models based on baseline/pre-vaccination variables

From: HAI and NAI titer correlates of inactivated and live attenuated influenza vaccine efficacy

 

LAIV

IIV

 

OR (95% CI)

P

OR (95% CI)

P

Vacc

0.69 (0.38, 1.25)

0.224

0.05 (0.01, 0.28)

0.001

Evervax

0.70 (0.24, 2.05)

0.512

0.25 (0.03, 1.96)

0.189

Day 0 HAI

0.84 (0.74, 0.96)

0.007

0.71 (0.60, 0.84)

0.000

Day 0 NAI

0.60 (0.46, 0.78)

0.000

0.37 (0.20, 0.71)

0.002

Evervax:Day 0 NAI

1.69 (1.17, 2.43)

0.005

2.97 (1.30, 6.78)

0.010

Vacc:Evervax

  

16.81 (0.99, 284.65)

0.051

Vacc:Day 0 NAI

  

2.73 (1.31, 5.71)

0.008

Vacc:Evervax:Day 0 NAI

  

0.23 (0.08, 0.66)

0.006

  1. ∗All models adjust for age, sex and race at baseline. Vacc = 1 or 0 if assigned vaccine or placebo; Evervax = 1 or 0 if self-reported ever having an influenza vaccination yes or no; HAI and NAI titers are log base 2 transformed. ∗∗Entries for two-way interactions (e.g., Vacc:Evervax) are ratios of odds ratios, and for three-way interactions (Vacc:Evervax:Day 0 NAI) are ratios of ratios of odds ratios