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Table 2 Distribution of constitutional symptoms reported at the time of inclusion, n (%)a

From: Evaluation of treatment response in extrapulmonary tuberculosis in a low-resource setting

  Total n = 126 Symptoms
Constitutionalb Fever Weight loss Night sweats Fatigue Loss of appetite
≥1 symptoms ≥3 symptoms
Diagnosis
 TB 64 50 (78%) 23 (36%) 33 (52%) 36 (57%) 21 (33%) 16 (26%) 20 (32%)
 Non-TB 62 42 (68%) 22 (35%) 26 (42%) 25 (42%) 18 (29%) 24 (39%) 18 (30%)
P valuec .189 .958 .279 .086 .604 .109 .741
TB cases
 Confirmed TB 12 9 (75%) 3 (25%) 6 (50%) 6 (50%) 3 (25%) 3 (27%) 4 (33%)
 Probable TB 34 28 (82%) 16 (47%) 21 (62%) 23 (70%) 12 (35%) 8 (24%) 13 (38%)
 Possible TB 18 13 (72%) 4 (22%) 6 (33%) 7 (39%) 6 (35%) 5 (29%) 3 (19%)
Site
 Lymphadenitis
  TB 34 22 (65%) 7 (21%) 14 (41%) 15 (45%) 7 (21%) 2 (6%) 5 (15%)
  Non-TB 33 15 (45%) 6 (18%) 9 (27%) 8 (25%) 4 (12%) 5 (16%) 7 (21%)
 Pleuritis
  TB 20 20 (100%) 12 (60%) 13 (65%) 16 (80%) 11 (55%) 9 (47%) 12 (63%)
  Non-TB 11 11 (100%) 6 (55%) 7 (64%) 6 (55%) 7 (64%) 8 (73%) 4 (40%)
 Other sites
  TB 10 8 (80%) 4 (40%) 6 (60%) 5 (50%) 3 (33%) 5 (50%) 3 (30%)
  Non-TB 18 16 (89%) 10 (56%) 10 (56%) 11 (65%) 7 (39%) 11 (61%) 7 (39%)
Age
 Children
  TB 16 12 (75%) 2 (13%) 8 (50%) 5 (31%) 6 (38%) 1 (6%) 0 (−)
  Non-TB 25 14 (56%) 6 (24%) 8 (32%) 6 (25%) 6 (24%) 7 (28%) 6 (25%)
 Adults
  TB 48 38 (79%) 21 (44%) 25 (52%) 31 (66%) 15 (32%) 15 (33%) 20 (43%)
  Non-TB 37 28 (76%) 16 (43%) 18 (49%) 19 (53%) 12 (32%) 17 (47%) 12 (32%)
HIV statusd
 HIV positive
  TB 14 13 (93%) 6 (43%) 8 (57%) 8 (62%) 5 (38%) 6 (46%) 6 (43%)
  Non-TB 6 6 (100%) 4 (67%) 6 (100%) 3 (60%) 1 (17%) 4 (67%) 3 (50%)
 HIV negative
  TB 46 33 (72%) 16 (35%) 21 (46%) 27 (59%) 14 (30%) 9 (20%) 14 (32%)
  Non-TB 28 20 (71%) 10 (36%) 11 (39%) 15 (54%) 8 (29%) 11 (39%) 8 (29%)
  1. Abbreviations: TB tuberculosis, HIV human immunodeficiency virus
  2. a Patients with missing values excluded
  3. b The following were included as constitutional symptoms; fever, weight loss, night sweats, fatigue, loss of appetite. ≥1 and ≥ 3 refers to number of patients reporting one or more or three or more symptoms respectively
  4. cP value < 0. 0071 (0.05/7) considered statistically significant
  5. d Patients with unknown HIV status excluded