Functional capacity of natural killer cells in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients

Table 1 Clinical and demographic characteristics of all individuals included in the study

Groups	Age (Years) Mean ± SD	Gender - n (%)		PVL	Spasticity in lower limbs	Overactive bladder
Groups	Age (Years) Mean ± SD	F	M	Median (IQR 25–75)	n (%)	n (%)
HAM/TSP (n = 20)	48.7 ± 10	13 (65.0)	7 (35.0)	173,146 (94,232-240,393)*	20 (100)	13 (76)^a
AS (n = 28)	42.9 ± 11.4	19 (67.9)	9 (32.1)	10,101 (1659-36,326)	0	0
CTR (n = 18)	41.4 ± 14.2	10 (55.6)	8 (44.4)	–	0	0

HAM/TSP HTLV-1-associated myelopathy/Tropical spastic paraparesis, AS Asymptomatic, CTR Uninfected controls, n Number, SD Standard Deviation, F Female, M Male, IQR Interquartile range, PVL HTLV-1 Proviral load (copies/10⁶ PBMC), performed for 14 patients with HAM/TSP and 24 asymtomatic individuals. ^aData available from only 17 HAM/TSP patients. Statistical analysis of differences between groups determined by the Kruskal-Wallis test, followed by Dunn’s post-test. Statistical analysis of proviral load performed using the Mann-Whitney test. *(p = 0.0001)

ISSN: 1471-2334