Table 2 Characteristics of included admissions overall and by site
Category | n (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
St. Petersburg | Moscow | Czech Republic | Turkey | France | Beijing | Valencia | Mexico | India | Curitiba | Total | |
N = 2071 | N = 1934 | N = 124 | N = 704 | N = 141 | N = 2157 | N = 2145 | N = 96 | N = 331 | N = 179 | N = 9882 | |
Age (y), median [IQR] | 2 [0–12] | 20 [3–29] | 48 [31–69] | 6 [0–65] | 66 [51–79] | 9 [3–66] | 70 [39–82] | 42 [20–58] | 37 [0–65] | 1 [0–6] | 20 [2–61] |
Age groupa | |||||||||||
0–1 y | 813 (39.3) | 239 (12.4) | 0 (0.0) | 247 (35.1) | 0 (0.0) | 309 (14.3) | 317 (14.8) | 7 (7.3) | 111 (33.5) | 102 (57.0) | 2145 (21.7) |
2–4 y | 550 (26.6) | 365 (18.9) | 0 (0.0) | 96 (13.7) | 0 (0.0) | 572 (26.5) | 82 (3.8) | 6 (6.3) | 13 (3.9) | 27 (15.1) | 1711 (17.3) |
5–17 y | 261 (12.6) | 228 (11.8) | 0 (0.0) | 69 (9.8) | 0 (0.0) | 258 (12.0) | 53 (2.5) | 10 (10.4) | 6 (1.8) | 23 (12.8) | 908 (9.2) |
18–49 y | 356 (17.2) | 1000 (51.7) | 66 (53.2) | 41 (5.8) | 32 (22.7) | 216 (10.0) | 190 (8.9) | 33 (34.4) | 59 (17.8) | 8 (4.5) | 2001 (20.2) |
50–64 y | 69 (3.3) | 67 (3.5) | 18 (14.5) | 70 (10.0) | 32 (22.7) | 239 (11.1) | 275 (12.8) | 23 (24.0) | 41 (12.4) | 13 (7.3) | 847 (8.6) |
65–74 y | 6 (0.3) | 15 (0.8) | 16 (12.9) | 59 (8.4) | 27 (19.1) | 244 (11.3) | 352 (16.4) | 4 (4.2) | 64 (19.3) | 5 (2.8) | 792 (8.0) |
75–84 y | 15 (0.7) | 17 (0.9) | 18 (14.5) | 85 (12.1) | 29 (20.6) | 260 (12.1) | 489 (22.8) | 11 (11.5) | 31 (9.4) | 1 (0.6) | 956 (9.7) |
≥ 85 y | 1 (< 0.1) | 3 (0.2) | 6 (4.8) | 36 (5.1) | 21 (14.9) | 59 (2.7) | 387 (18.0) | 2 (2.1) | 6 (1.8) | 0 (0.0) | 521 (5.3) |
Sex | |||||||||||
Male | 1180 (57.0) | 1002 (51.8) | 67 (54.0) | 378 (53.7) | 63 (44.7) | 1223 (56.7) | 1151 (53.7) | 42 (43.8) | 180 (54.4) | 94 (52.5) | 5380 (54.4) |
Female | 891 (43.0) | 932 (48.2) | 57 (46.0) | 326 (46.3) | 78 (55.3) | 934 (43.3) | 994 (46.3) | 54 (56.3) | 151 (45.6) | 85 (47.5) | 4502 (45.6) |
Chronic conditions | |||||||||||
0 | 1872 (90.4) | 1718 (88.8) | 60 (48.4) | 337 (47.9) | 42 (29.8) | 1529 (70.9) | 742 (34.6) | 32 (33.3) | 156 (47.1) | 118 (65.9) | 6606 (66.8) |
1 | 164 (7.9) | 172 (8.9) | 37 (29.8) | 177 (25.1) | 47 (33.3) | 406 (18.8) | 611 (28.5) | 29 (30.2) | 84 (25.4) | 40 (22.3) | 1767 (17.9) |
> 1 | 35 (1.7) | 44 (2.3) | 27 (21.8) | 190 (27.0) | 52 (36.9) | 222 (10.3) | 792 (36.9) | 35 (36.5) | 91 (27.5) | 21 (11.7) | 1509 (15.3) |
Hospitalized within ≤12 mo | |||||||||||
No | 1408 (68.0) | 1577 (81.5) | 99 (79.8) | 385 (54.7) | 76 (53.9) | 1774 (82.2) | 1448 (67.5) | 62 (64.6) | 202 (61.0) | 137 (76.5) | 7168 (72.5) |
Yes | 663 (32.0) | 357 (18.5) | 25 (20.2) | 319 (45.3) | 65 (46.1) | 383 (17.8) | 697 (32.5) | 34 (35.4) | 129 (39.0) | 42 (23.5) | 2714 (27.5) |
Underlying conditions | |||||||||||
Cardiovascular disease | 59 (2.8) | 100 (5.2) | 38 (30.6) | 219 (31.1) | 60 (42.6) | 427 (19.8) | 842 (39.3) | 30 (31.3) | 94 (28.4) | 19 (10.6) | 1888 (19.1) |
Chronic obstructive pulmonary disease | 21 (1.0) | 18 (0.9) | 4 (3.2) | 98 (13.9) | 30 (21.3) | 252 (11.7) | 510 (23.8) | 7 (7.3) | 85 (25.7) | 14 (7.8) | 1039 (10.5) |
Asthma | 44 (2.1) | 19 (1.0) | 10 (8.1) | 60 (8.5) | 8 (5.7) | 52 (2.4) | 170 (7.9) | 14 (14.6) | 18 (5.4) | 29 (16.2) | 424 (4.3) |
Immunodeficiency/organ transplant | 11 (0.5) | 0 (0.0) | 6 (4.8) | 33 (4.7) | 8 (5.7) | 1 (< 0.1) | 19 (0.9) | 10 (10.4) | 3 (0.9) | 1 (0.6) | 92 (0.9) |
Diabetes | 14 (0.7) | 19 (1.0) | 16 (12.9) | 88 (12.5) | 28 (19.9) | 98 (4.5) | 515 (24.0) | 12 (12.5) | 37 (11.2) | 13 (7.3) | 840 (8.5) |
Chronic renal impairment | 14 (0.7) | 54 (2.8) | 6 (4.8) | 54 (7.7) | 22 (15.6) | 15 (0.7) | 247 (11.5) | 16 (16.7) | 26 (7.9) | 0 (0.0) | 454 (4.6) |
Chronic neuromuscular disease | 47 (2.3) | 19 (1.0) | 3 (2.4) | 59 (8.4) | 4 (2.8) | 22 (1.0) | 38 (1.8) | 7 (7.3) | 5 (1.5) | 8 (4.5) | 212 (2.1) |
Active neoplasm | 6 (0.3) | 8 (0.4) | 12 (9.7) | 57 (8.1) | 18 (12.8) | 28 (1.3) | 148 (6.9) | 4 (4.2) | 22 (6.6) | 1 (0.6) | 304 (3.1) |
Chronic liver disease | 15 (0.7) | 21 (1.1) | 3 (2.4) | 8 (1.1) | 4 (2.8) | 9 (0.4) | 73 (3.4) | 3 (3.1) | 1 (0.3) | 0 (0.0) | 137 (1.4) |
Autoimmune disease | 13 (0.6) | 15 (0.8) | 4 (3.2) | 10 (1.4) | 0 (0.0) | 8 (0.4) | 27 (1.3) | 11 (11.5) | 14 (4.2) | 2 (1.1) | 104 (1.1) |
Pregnant (women 15–45 y) | 0 (0.0) | 596 (30.8) | 2 (1.6) | 2 (0.3) | 4 (2.8) | 0 (0.0) | 3 (0.1) | 0 (0.0) | 4 (1.2) | 4 (2.2) | 615 (6.2) |
Obeseb,c | 202 (9.8) | 200 (10.3) | 36 (29.0) | 116 (19.5) | 23 (16.3) | 238 (11.0) | 529 (24.7) | 25 (26.3) | 31 (9.4) | 25 (14.0) | 1425 (14.4) |
Outpatient consultations within ≤3 mod | |||||||||||
0 | 927 (44.8) | 655 (33.9) | 43 (34.7) | 164 (23.3) | 17 (12.1) | 1039 (48.2) | 214 (10.0) | 38 (39.6) | 46 (13.9) | 47 (26.3) | 2151 (21.8) |
1 | 660 (31.9) | 447 (23.1) | 34 (27.4) | 186 (26.4) | 54 (38.6) | 1022 (47.4) | 246 (11.5) | 18 (18.8) | 54 (16.3) | 74 (41.3) | 2812 (28.5) |
≥ 2 | 484 (23.4) | 832 (43.0) | 47 (37.9) | 354 (50.3) | 69 (49.3) | 96 (4.45) | 1685 (78.6) | 40 (41.7) | 231 (69.8) | 58 (32.4) | 4918 (49.8) |
Smoking habits (≥ 18 y)e | |||||||||||
Never smoked | 221 (49.4) | 571 (51.8) | 70 (56.5) | 153 (58.0) | 64 (45.4) | 570 (56.0) | 749 (44.2) | 39 (53.4) | 103 (51.2) | 8 (29.6) | 2548 (50.1) |
Past smoker | 57 (12.8) | 249 (22.6) | 15 (12.1) | 87 (33.0) | 41 (29.1) | 270 (26.5) | 569 (33.6) | 29 (39.7) | 74 (36.8) | 13 (48.1) | 1404 (27.6) |
Current smoker | 169 (37.8) | 282 (25.6) | 39 (31.5) | 24 (9.1) | 36 (25.5) | 178 (17.5) | 375 (22.2) | 5 (6.8) | 24 (11.9) | 6 (22.2) | 1138 (22.4) |
Functional impairment status (Barthel index, patients ≥65 y)f | |||||||||||
Total (0–15) | 0 (0.0) | 0 (0.0) | 1 (2.5) | 21 (11.7) | 0 (0.0) | 37 (11.8) | 116 (9.5) | 0 (0.0) | 5 (5.1) | 0 (0.0) | 180 (8.9) |
Severe (20–35) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 12 (6.7) | 1 (1.3) | 10 (3.2) | 45 (3.7) | 1 (5.9) | 8 (8.2) | 0 (0.0) | 77 (3.8) |
Moderate (40–55) | 0 (0.0) | 0 (0.0) | 1 (2.5) | 14 (7.8) | 4 (5.2) | 38 (12.1) | 72 (5.9) | 2 (11.8) | 23 (23.5) | 0 (0.0) | 154 (7.7) |
Mild (60–90) | 4 (18.2) | 7 (20.0) | 5 (12.5) | 71 (39.7) | 16 (20.8) | 172 (55.0) | 230 (18.7) | 8 (47.1) | 41 (41.8) | 0 (0.0) | 554 (27.5) |
Minimal (95–100) | 18 (81.8) | 28 (80.0) | 33 (82.5) | 61 (34.1) | 56 (72.7) | 56 (17.9) | 764 (62.3) | 6 (35.3) | 21 (21.4) | 5 (100.0) | 1048 (52.1) |
Time from onset of symptoms to swabbing | |||||||||||
0–2 d | 1102 (53.2) | 1025 (53.1) | 41 (33.1) | 133 (19.1) | 63 (44.7) | 503 (23.3) | 446 (20.8) | 17 (17.9) | 34 (10.3) | 37 (20.7) | 3401 (34.5) |
3–4 d | 656 (31.7) | 619 (32.1) | 46 (37.1) | 251 (36.1) | 41 (29.1) | 628 (29.1) | 820 (38.3) | 22 (23.2) | 130 (39.3) | 98 (54.7) | 3311 (33.6) |
5–7 d | 313 (15.1) | 281 (14.6) | 36 (29.0) | 301 (43.2) | 37 (26.2) | 899 (41.7) | 681 (31.8) | 48 (50.5) | 164 (49.5) | 43 (24.0) | 2803 (28.4) |
8–9 d | 0 (0.0) | 4 (0.2) | 1 (0.8) | 11 (1.6) | 0 (0.0) | 126 (5.8) | 196 (9.1) | 8 (8.4) | 3 (0.9) | 1 (0.6) | 350 (3.5) |
> 10 or missing | – | 5 | – | 8 | – | 1 | 2 | 1 | – | – | 17 |
Vaccinated for influenza during 2015–2016g | 45 (2.2) | 87 (4.5) | 7 (5.6) | 49 (7.0) | 60 (42.6) | 262 (12.1) | 923 (43.0) | 19 (19.8) | 15 (4.5) | 58 (32.4) | 1525 (15.4) |
≥ 14 d from ILI onseth | 45 (100.0) | 87 (100.0) | 7 (100.0) | 41 (83.7) | 60 (100.0) | 260 (99.2) | 912 (98.8) | 5 (26.3) | 15 (100.0) | 46 (79.3) | 1478 (96.9) |