Skip to main content

Table 3 Effect of BMI on immune reconstitution outcome of CD4 more than 500cells/μL during the follow-up after antiretroviral therapy

From: Predictive effects of body mass index on immune reconstitution among HIV-infected HAART users in China

Covariate

HR (95% CI)

p

Adjusted HR (95% CI)

p

Continuous BMI

1.06 (1.03 to 1.08)

< 0.01

1.03 (1.01 to 1.06)

0.011

Sex (female vs male)

0.78 (0.56 to 1.07)

0.118

–

–

Age

0.98 (0.97 to 0.98)

< 0.01

0.99 (0.98 to 1.00)

0.004

Baseline CD4 (per 100cells/μL increase)

 1–100

Ref

 

Ref

 

 101–200

3.03 (1.95 to 4.70)

< 0.01

2.92 (1.78 to 4.78)

< 0.01

 201–300

10.36 (6.91 to 15.52)

< 0.01

10.38 (6.40 to 16.82)

< 0.01

 301–400

25.82 (17.12 to 38.93)

< 0.01

25.42 (15.48 to 41.75)

< 0.01

 401–499

56.37 (36.40 to 87.30)

< 0.01

52.06 (30.75 to 88.13)

< 0.01

 CD4/CD8 ratio

16.07 (11.67 to 22.12)

< 0.01

2.47 (1.47 to 4.13)

0.001

Baseline viral load (per log10 increase) (copies/mL)

  ≤ 3.00

Ref

 

Ref

 

  ≥ 6.01

0.53 (0.23 to 1.25)

0.147

4.60 (1.90 to 11.16)

0.001

 5.01–6.00

0.83 (0.44 to 1.57)

0.569

2.62 (1.37 to 4.99)

0.004

 4.01–5.00

1.22 (0.65 to 2.28)

0.540

1.97 (1.05 to 3.72)

0.035

 3.01–4.00

1.53 (0.80 to 2.92)

0.201

1.68 (0.87 to 3.22)

0.120

WHO stage

 I

Ref

 

Ref

 

 II

0.41 (0.27 to 0.63)

< 0.01

0.62 (0.40 to 0.97)

0.037

 III

0.34 (0.23 to 0.51)

< 0.01

0.67 (0.44 to 1.04)

0.074

 IV

0.22 (0.14 to 0.33)

< 0.01

1.09 (0.68 to 1.75)

0.736

Drinking (yes vs no)

1.04 (0.90 to 1.20)

0.593

–

–

Race (not Han vs Han)

0.98 (0.79 to 1.21)

0.834

–

–

  1. CI confidence intervals, HR hazard ratios, Ref reference