Is HBV viral load at admission associated with development of acute-on-chronic liver failure in patients with acute decompensation of chronic hepatitis B related cirrhosis?

Table 2 Serum HBV DNA ad-levels of the patients who developed to ACLF or not

Groups	n	HBV DNA (IU/ml), n (%)						Log (HBV DNA), mean ± SD
Groups	n	<10	≥10	<2000	≥2000	<2 × 10⁶	≥2 × 10⁶	Log (HBV DNA), mean ± SD
Non-ACLF	68	4 (5.9)	64 (94.1)	22 (32.4)	46 (67.6)	56(82.4)	12(17.6)	4.32 ± 1.99
ACLF before admission	26	1 (3.80)	25 (96.2)	7 (26.9)	19 (73.1)	20(76.9)	6(23.1)	4.65 ± 1.99
ACLF after admission	17	0 (0.0)	17 (100.0)	7(41.2)	10 (58.8)	15(88.2)	2(11.8)	4.27 ± 1.94
Total	111	5 (4.5)	106 (95.5)	36 (32.4)	75 (67.6)	91(82.0)	20(18.0)	4.39 ± 1.97

1. Groups: Non-ACLF, patients without ACLF development; ACLF, patients with ACLF development;
2. HBV DNA <10 IU/ml or ≥ 10 IU/ml: Fisher’s exact test, P = 0.827
3. HBV DNA <2000 IU/ml or ≥ 2000 IU/ml: χ² = 0.953, P = 0.597
4. HBV DNA <2 × 10⁶ IU/ml or ≥ 2 × 10⁶ IU/ml: Fisher’s exact test, P = 0.643
5. Log(HBV DNA) (logarithm of the serum HBV DNA ad-level): F = 0.304, P = 0.739

ISSN: 1471-2334