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Table 4 Association of drug resistance with genotype of M. tuberculosis isolates from TB patients, South Gondar Zone, Amhara region, northwest Ethiopia (2015–2017)

From: Molecular detection of Mycobacterium tuberculosis sensitivity to rifampicin and isoniazid in South Gondar Zone, northwest Ethiopia

Characteristics Variables Any drug resistance Total χ2(df) p- value
Yes No
Major lineage EA 16 43 59 9.67 (4) 0.046
EAI 0 25 25   
EAS 0 1 1   
IO 0 2 2   
M. africanum 1 7 8   
Sublineages/clades AFRI 0 7 7 14.1 (8) 0.080
Beijing 0 1 1   
CAS 0 23 23   
H 1 6 7   
Manu 3 7 10   
T 10 20 30   
T3-ETH 4 10 14   
Turkey 0 3 3   
X 0 1 1   
Dominant strains Orphan 6 14 20 4.30 (3) 0.23`
SIT53 4 14 18   
SIT149 3 9 12   
SIT428 0 12 12   
Clustering No 5 20 25 0.34 (1) 0.852
Yes 13 58 71   
  1. EA Euro-American, EAI East-African-Indian, IO Indo-Oceanic, EAS East-African-Asian, CAS Central Asian Strain, H Harlem, AFRI African, SIT shared international types. χ2 Chi-square, df degree of freedom