Table 4 Association of drug resistance with genotype of M. tuberculosis isolates from TB patients, South Gondar Zone, Amhara region, northwest Ethiopia (2015ā2017)
Characteristics | Variables | Any drug resistance | Total | Ļ2(df) | p- value | |
|---|---|---|---|---|---|---|
Yes | No | |||||
Major lineage | EA | 16 | 43 | 59 | 9.67 (4) | 0.046 |
EAI | 0 | 25 | 25 | Ā | Ā | |
EAS | 0 | 1 | 1 | Ā | Ā | |
IO | 0 | 2 | 2 | Ā | Ā | |
M. africanum | 1 | 7 | 8 | Ā | Ā | |
Sublineages/clades | AFRI | 0 | 7 | 7 | 14.1 (8) | 0.080 |
Beijing | 0 | 1 | 1 | Ā | Ā | |
CAS | 0 | 23 | 23 | Ā | Ā | |
H | 1 | 6 | 7 | Ā | Ā | |
Manu | 3 | 7 | 10 | Ā | Ā | |
T | 10 | 20 | 30 | Ā | Ā | |
T3-ETH | 4 | 10 | 14 | Ā | Ā | |
Turkey | 0 | 3 | 3 | Ā | Ā | |
X | 0 | 1 | 1 | Ā | Ā | |
Dominant strains | Orphan | 6 | 14 | 20 | 4.30 (3) | 0.23` |
SIT53 | 4 | 14 | 18 | Ā | Ā | |
SIT149 | 3 | 9 | 12 | Ā | Ā | |
SIT428 | 0 | 12 | 12 | Ā | Ā | |
Clustering | No | 5 | 20 | 25 | 0.34 (1) | 0.852 |
Yes | 13 | 58 | 71 | Ā | Ā | |