BMC Infectious Diseases

Table 3 Distribution of target gene mutations and resistance patterns in anti-TB drug resistant M. tuberculosis isolates, South Gondar Zone, Amhara region, northwest Ethiopia (2015–2017)

From: Molecular detection of Mycobacterium tuberculosis sensitivity to rifampicin and isoniazid in South Gondar Zone, northwest Ethiopia

		Target genes
Isolates	rpoB	rpoB katG	lnhA	Type of mutation	Drug resistance pattern
FE31	WT1–8	MUT 1	WT1,2	specific	RIFs INHr
FE34	WT1–8	MUT1	WT1,2	specific	RIFs INHr
FE50	WT1–8	WT, MUT 1	WT1,2	rare	RIFs INHr^a
FE51	WT1–8	MUT1	WT1,2	specific	RIFs INHr
FE54	WT1–8	MUT1	WT1,2	specific	RIFs INHr
FE55	WT1–8	MUT1	WT1,2	specific	RIFs INHr
FE56	WT1–8	WT, MUT1	WT1,2	rare	RIFs INHr^a
FE72	WT1–8	WT, MUT1	WT1,2	rare	RIFs INHr^a
FE74	WT1–8	MUT1	WT1,2	specific	RIFs INHr
FP12	WT1–8	WT, MUT1	WT1,2	rare	RIFs INHr^a
WHC02	WT1–8	MUT1	WT1,2	specific	RIFs INHr
WHC13	WT1–8	MUT1	WT1,2	specific	RIFs INHr
WHC14	WT1–8	MUT1	WT1,2	specific	RIFs INHr
WHC405	WT1–8	WT, MUT1	WT1,2	rare	RIFs INHr^a
WHC322	WT1–6, 8,	MUT1	WT1,2	unknown	RIFr INHr^b
WHC710	WT1–6, 8,	MUT1	WT1,2	unknown	RIFr INHr^b
AZ05	WT1–8	WT, MUT1	WT1,2	rare	RIFs INHr^a
AZ06	WT1–8	MUT1	WT1,2	specific	RIFs INHr
WHN02	WT1–8	MUT1	WT1,2	specific	RIFs INHr
255A	WT1–8	MUT1	WT1,2	specific	RIFs INHr

^aHetroresistance, ^bMultidrug resistance
WT Wild type, MUT Mutant type; the subscripts ‘s’ and ‘r’ refer to: sensitive and resistance, respectively

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ISSN: 1471-2334

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