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Table 3 Distribution of target gene mutations and resistance patterns in anti-TB drug resistant M. tuberculosis isolates, South Gondar Zone, Amhara region, northwest Ethiopia (2015–2017)

From: Molecular detection of Mycobacterium tuberculosis sensitivity to rifampicin and isoniazid in South Gondar Zone, northwest Ethiopia

  Target genes  
Isolates rpoB rpoB katG lnhA Type of mutation Drug resistance pattern
FE31 WT1–8 MUT 1 WT1,2 specific RIFs INHr
FE34 WT1–8 MUT1 WT1,2 specific RIFs INHr
FE50 WT1–8 WT, MUT 1 WT1,2 rare RIFs INHra
FE51 WT1–8 MUT1 WT1,2 specific RIFs INHr
FE54 WT1–8 MUT1 WT1,2 specific RIFs INHr
FE55 WT1–8 MUT1 WT1,2 specific RIFs INHr
FE56 WT1–8 WT, MUT1 WT1,2 rare RIFs INHra
FE72 WT1–8 WT, MUT1 WT1,2 rare RIFs INHra
FE74 WT1–8 MUT1 WT1,2 specific RIFs INHr
FP12 WT1–8 WT, MUT1 WT1,2 rare RIFs INHra
WHC02 WT1–8 MUT1 WT1,2 specific RIFs INHr
WHC13 WT1–8 MUT1 WT1,2 specific RIFs INHr
WHC14 WT1–8 MUT1 WT1,2 specific RIFs INHr
WHC405 WT1–8 WT, MUT1 WT1,2 rare RIFs INHra
WHC322 WT1–6, 8, MUT1 WT1,2 unknown RIFr INHrb
WHC710 WT1–6, 8, MUT1 WT1,2 unknown RIFr INHrb
AZ05 WT1–8 WT, MUT1 WT1,2 rare RIFs INHra
AZ06 WT1–8 MUT1 WT1,2 specific RIFs INHr
WHN02 WT1–8 MUT1 WT1,2 specific RIFs INHr
255A WT1–8 MUT1 WT1,2 specific RIFs INHr
  1. aHetroresistance, bMultidrug resistance
  2. WT Wild type, MUT Mutant type; the subscripts ‘s’ and ‘r’ refer to: sensitive and resistance, respectively