Clinical outcomes | Overall series | Propensity score-matched pairs | ||||
---|---|---|---|---|---|---|
PHAP (n = 97) | CAP (n = 607) | P value | PHAP (n = 88) | CAP (n = 88) | P value | |
Duration of antibiotic therapy (days) | 10 (7–12) | 10 (7–13) | 0.536 | 10 (7–12) | 10 (7–14) | 0.426 |
Change of antibiotics | 17 (17.5) | 122 (20.0) | 0.554 | 16 (18.2) | 25 (28.4) | 0.109 |
Escalation | 1 (1.0) | 12 (2.0) | 1.000 | 1 (1.1) | 3 (3.4) | 0.621 |
De-escalation | 16 (16.5) | 110 (18.1) | 0.698 | 15 (17.0) | 22 (25.0) | 0.195 |
Use of inappropriate antibioticsa | 4 (12.1) | 39 (19.4) | 0.317 | 4 (4.5) | 9 (10.2) | 0.150 |
Failure of initial antibiotic therapy | 20 (20.6) | 113 (18.6) | 0.640 | 17 (19.3) | 23 (26.1) | 0.280 |
Length of hospital stay (days) | 9 (6–14) | 7 (5–11) | 0.001 | 9 (6–13) | 8 (6–15) | 0.871 |
30-day mortality rate | 13 (13.4) | 43 (7.0) | 0.033 | 9 (10.2) | 13 (14.8) | 0.362 |
Total in-hospital mortality rate | 17 (17.5) | 48 (7.8) | 0.002 | 12 (13.6) | 14 (15.9) | 0.671 |