Table 2 Isolated germs, involved body regions, fatalities, and reconstructive procedures in case-control studies and pooled cases
From: A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018
| Item | Zerr et al. [30] | Hsieh et al. [31] | Pooled cases [2–4, 8, 27, 32–221] |
|---|---|---|---|
| Group-A streptococci [%] (Number) | 84.2 (16/19) | 87.5 (7/8) | 44.8 (132/295) |
| Staphylococcus aureus [%] (Number) | 5.3 (1/19) | 12.5 (1/8) | 18.6 (55/295) |
| Gramnegative rods combined [%] (Number) | 0 | 0 | 29.8 (88/295) |
| Pseudomonas aeruginosa [%] (Number) | 0 | 0 | 10.2 (30/295) |
| Escherichia coli [%] (Number) | 0 | 0 | 7.8 (23/295) |
| Serratia marcescens [%] (Number) | 0 | 0 | 1.7 (5/295) |
| Klebsiella species [%] (Number) | 0 | 0 | 1.7 (5/295) |
| Other gramnegative rods [%] (Number) | 0 | 0 | 8.5 (25/295) |
| Anaerobe microbes [%] (Number) | 0 | 0 | 7.1 (21/295) |
| Other streptococci [%] (Number) | 0 | 0 | 6.8 (20/295) |
| Fungi [%] (Number) | 0 | 0 | 3.4 (10/295) |
| Other staphylococci [%] (Number) | 0 | 0 | 3.1 (9/295) |
| Enterococcus species [%] (Number) | 0 | 0 | 2.7 (8/295) |
| Polymicrobial infection [%] (Number) | 5.3 (1/19) | 0 | 17.3 (51/295) |
| Extremities [%] (Number) | 63.2 (12/19) | Not reported | 45.6 (136/298) |
| Lower extremity [%] (Number) | Not reported | Not reported | 33.9 (100/298) |
| Upper extremity [%] (Number) | Not reported | Not reported | 12.1 (36/298) |
| Trunk [%] (Number) | 21.1 (4/19) | Not reported | 32.9 (98/298) |
| Head [%] (Number) | 15.8 (3/19) | Not reported | 20.8 (62/298) |
| Retroperitoneum [%] (Number) | 0 | Not reported | 0.7 (2/298) |
| Second body region involved [%] (Number) | 0 | Not reported | 16.8 (50/298) |
| Lower extremity [%] (Number) | 0 | Not reported | 11.1 (33/298) |
| Trunk [%] (Number) | 0 | Not reported | 3.7 (11/298) |
| Upper extremity [%] (Number) | 0 | Not reported | 2 (6/298) |
| More than two body regions involved [%] (Number) | 0 | Not reported | 2.7 (8/298) |
| Fatalities [%] (Number) | 0 | 0 | 10.4 (31/295) |
| Primary closure [%] (Number) | Not reported | Not reported | 17.3 (28/162) |
| Secondary closure [%] (Number) | Not reported | Not reported | 20.4 (33/162) |
| Skin graft [%] (Number) | Not reported | Not reported | 51.6 (84/162) |
| Skin flap [%] (Number) | Not reported | Not reported | 10.5 (17/162) |