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Table 2 Isolated germs, involved body regions, fatalities, and reconstructive procedures in case-control studies and pooled cases

From: A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018

Item Zerr et al. [30] Hsieh et al. [31] Pooled cases [24, 8, 27, 32221]
Group-A streptococci [%] (Number) 84.2 (16/19) 87.5 (7/8) 44.8 (132/295)
Staphylococcus aureus [%] (Number) 5.3 (1/19) 12.5 (1/8) 18.6 (55/295)
Gramnegative rods combined [%] (Number) 0 0 29.8 (88/295)
Pseudomonas aeruginosa [%] (Number) 0 0 10.2 (30/295)
Escherichia coli [%] (Number) 0 0 7.8 (23/295)
Serratia marcescens [%] (Number) 0 0 1.7 (5/295)
Klebsiella species [%] (Number) 0 0 1.7 (5/295)
Other gramnegative rods [%] (Number) 0 0 8.5 (25/295)
Anaerobe microbes [%] (Number) 0 0 7.1 (21/295)
Other streptococci [%] (Number) 0 0 6.8 (20/295)
Fungi [%] (Number) 0 0 3.4 (10/295)
Other staphylococci [%] (Number) 0 0 3.1 (9/295)
Enterococcus species [%] (Number) 0 0 2.7 (8/295)
Polymicrobial infection [%] (Number) 5.3 (1/19) 0 17.3 (51/295)
Extremities [%] (Number) 63.2 (12/19) Not reported 45.6 (136/298)
Lower extremity [%] (Number) Not reported Not reported 33.9 (100/298)
Upper extremity [%] (Number) Not reported Not reported 12.1 (36/298)
Trunk [%] (Number) 21.1 (4/19) Not reported 32.9 (98/298)
Head [%] (Number) 15.8 (3/19) Not reported 20.8 (62/298)
Retroperitoneum [%] (Number) 0 Not reported 0.7 (2/298)
Second body region involved [%] (Number) 0 Not reported 16.8 (50/298)
Lower extremity [%] (Number) 0 Not reported 11.1 (33/298)
Trunk [%] (Number) 0 Not reported 3.7 (11/298)
Upper extremity [%] (Number) 0 Not reported 2 (6/298)
More than two body regions involved [%] (Number) 0 Not reported 2.7 (8/298)
Fatalities [%] (Number) 0 0 10.4 (31/295)
Primary closure [%] (Number) Not reported Not reported 17.3 (28/162)
Secondary closure [%] (Number) Not reported Not reported 20.4 (33/162)
Skin graft [%] (Number) Not reported Not reported 51.6 (84/162)
Skin flap [%] (Number) Not reported Not reported 10.5 (17/162)