Skip to main content

Table 1 Age, risk factors, skin symptoms, and signs of systemic illness in case-control studies and pooled cases

From: A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018

Item Zerr et al. [30] Hsieh et al. [31] Pooled cases [24, 8, 27, 32221]
Age [years] (range) 4.6 (0.5-9.6) 5 (2-13) 5.7 (0.1-17)
Varicella [%] (Number) 100 (19/19) 50 (4/8) 25.9 (77/297)
No risk factor [%] (Number) 0 12.5 (1/8) 22.9 (68/297)
Minor trauma [%] (Number) 0 0 12.5 (37/297)
Immunocompromise [%] (Number) 0 0 11.8 (35/297)
Surgery [%] (Number) 0 12.5 (1/8) 9.4 (28/297)
Trauma [%] (Number) 0 25 (2/8) 8.1 (24/297)
Skin infection [%] (Number) 0 0 6.1 (18/297)
Intramuscular injection [%] (Number) 0 0 1.7 (5/297)
Neuropathy [%] (Number) 0 0 1.4 (4/297)
Diabetes [%] (Number) 0 0 0.4 (1/297)
Erythema [%] (Number) 94.7 (18/19) 87.5 (7/8) 58.7 (175/298)
Swelling [%] (Number) 100 (19/19) 87.5 (7/8) 48 (143/298)
Pain [%] (Number) 100 (19/19) 87.5 (7/8) 33.6 (100/298)
Splinting [%] (Number) 66.7 (12/18) 37.5 (3/8) 3 (9/298)
Tenderness [%] (Number) 0 37.5 (3/8) 25.2 (75/298)
Discolouration [%] (Number) 0 0 32.6 (97/298)
Necrosis [%] (Number) 0 0 32.2 (96/298)
Oedema [%] (Number) 0 0 26.5 (79/298)
Induration [%] (Number) 0 0 14.4 (43/298)
Warmth [%] (Number) 0 0 10.7 (32/298)
Bullae [%] (Number) 0 0 9.1 (27/298)
Discharge [%] (Number) 0 0 8.4 (25/298)
Ecchymosis [%] (Number) 0 0 8.4 (25/298)
Blister [%] (Number) 0 0 6 (18/298)
Crepitus [%] (Number) 0 0 3.7 (11/298)
Fever [%] (Number) 100 (19/19) Not reported 76.7 (188/245)
Tachycardia [%] (Number) 0 Not reported 40.7 (94/231)
Tachypnea [%] (Number) 0 Not reported 27.7 (64/231)
Hypotension [%] (Number) 26.3 (5/19) Not reported 29.9 (69/231)
Leukocytosis [%] (Number) Not reported Not reported 49.5 (106/214)
Bandemia [%] (Number) Not reported Not reported 22.9 (49/214)
Leukopenia [%] (Number) Not reported Not reported 17.3 (29/214)
Hypothermia [%] (Number) 0 Not reported 0.8 (2/245)
Bradycardia [%] (Number) 0 Not reported 0.4 (1/231)
Systemic inflammatory response syndrome [%] (Number) Not reported Not reported 65.1 (175/269)