Skip to main content

Table 2 Genotype findings of the patient at all loci tested. Homozygous potential deleterious variants were observed for four genes: IRAK1, MIF, ACE involved in inflammation and PAI-1 in thrombotic events

From: Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report

Gene name

Ref

WT/WT

WT/M

M/M

PAI-1

rs1799768

  

x

MIF

rs755622

  

x

ACE

rs17326674

  

x

IL-6

rs1800795

x

  

TNF

rs1800750

x

  
 

rs1800629

x

  
 

rs361525

x

  
 

rs909253

x

  

TLR2

rs5743708

x

  

TLR2

rs5743704

x

  

TLR4

rs4986790

x

  

TLR5

rs5744168

x

  

IRAK1

rs1059703

  

x

IKB

rs2233406

x

  
 

rs3138053

x

  

FcgammaRIIA

rs1801274

x

  

CFH

rs1065489

x

  
  1. PAI-1 Plasminogen activator inhibitor 1, MIF Macrophage migration inhibitor factor, ACE Angiotensin converting enzyme, IL-6 Interleukin 6, TNF Tumor Necrosis Factor, TLR Toll like receptor, IRAK1 Interleukin-1 receptor associated kinase, IΚB Inhibitory protein of nuclear factor-κB, FCgammaRIIA Fc receptor for IgG, CFH Complement factor H, WT Wild type concerns the frequent allele, M Mutation concerns the variant rare allele, Ref Reference number for the studied SNP