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Table 4 Predictors of poor treatment outcomes: simple and multiple logistic regression analysis

From: Treatment outcomes of drug resistant tuberculosis patients in Morocco: multi-centric prospective study

Independent variable

Treatment outcomes, n (%)

Univariate analysis

Multivariate analysis

Poor treatment(n = 47)

Successful treatment(n = 54)

P value

OR

95% CI

P value

Adjusted OR

95% CI

Age < =40 years

 

 No

20 (54.1)

17 (45.9)

 

1

  

1

 

 Yes

27 (42.2)

37 (57.8)

0.251

0.620

[0.275–1.401]

0.535

0.704

[0.232–2.136]

Gender

 

 Female

7 (24.1)

22 (75.9)

 

1

  

1

 

 Male

40 (55.6)

32 (44.4)

0.006

3.929

[1.490–10.356]

0.231

2.215

[0.602–8.151]

Residence

 

 Rural

8 (38.1)

13 (61.9)

 

1

  

1

 

 Urban

39 (48.8)

41 (51.2)

0.386

1.546

[0.578–4.134]

0.350

1.943

[0.483–7.820]

Employment

 

 Yes

13 (54.2)

11 (45.8)

 

1

  

1

 

 No

23 (46.0)

27 (54.0)

0.511

0.721

[0.271–1.914]

0.388

1.753

[0.491–6.263]

PTB+ at baseline

 

 No

8 (42.1)

11 (57.9)

 

1

  

1

[0.327-

 Yes

39 (47.6)

43 (52.4)

0.668

1.247

[0.455–3.419]

0.599

1.506

6.937]

Previous TB history

7 (41.2)

10 (58.8)

 

1

  

1

 

 No

40 (47.6)

44 (52.4)

0.628

1.299

[0.452–3.736]

0.671

0.707

[0.143–3.501]

 Yes

        

Smoking habits

 

 No

23 (33.3)

46 (66.7)

 

1

  

1

 

 Yes

24 (75.0)

8 (25.0)

< 0.001

6.00

[2.335–15.418]

0.015

4.355

[1.327–14. 292]

Comorbidity

 

 No

40 (49.4)

41 (50.6)

 

1

  

1

 

 Yes

7 (35.0)

13 (65.0)

0.252

0.552

[0.200–1.526]

0.902

1.090

[0.277–4.293]

  1. In bold: p value less than 0.05, TB: Tuberculosis; PTB+: smear positive pulmonary tuberculosis; OR: odds ratio; CI: confidence interval;1:reference
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BMC Infectious Diseases

ISSN: 1471-2334

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