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Table 3 Treatment related characteristics of HIV infected patients treated at Woldia and Dessie hospitals, 2018

From: Predictors of virological treatment failure among adult HIV patients on first-line antiretroviral therapy in Woldia and Dessie hospitals, Northeast Ethiopia: a case-control study

Variables Category Cases(n=154) Controls (n=154) p-value for Chi-square test
Frequency (%) Frequency (%)
Duration on ART <24 months 8 (5.2) 9 (5.8) 0.781
24-48 months 22 (14.3) 26 (16.9)
>48 months 124 (80.5) 119 (77.3)
Adherence level to ART treatment Good 89 (57.8) 135 (87.7) <0.001
Poor 65 (42.2) 19 (12.3)
History of CPT Yes 139 (90.3) 127 (82.5) 0.046
No 15 (9.7) 27 (17.5)
History of IPT Yes 8 (5.2) 16 (10.4) 0.089
No 146 (94.8) 138 (89.6)
Regimen at the start of ART d4t+3TC+NVP 32 (20.8) 26 (16.9) 0.931
AZT+3TC+NVP 46 (29.9) 50 (32.5)
AZT+3TC+EFV 30 (19.5) 30 (19.5)
TDF+3TC+EFV 37 (24) 38 (24.7)
TDF+3TC+NVP 9 (5.8) 10 (6.5)
First line regimen currently AZT+3TC+NVP 53 (34.4) 58 (37.7) 0.733
AZT+3TC+EFV 32 (20.8) 31 (20)
TDF+3TC+EFV 48 (31.2) 50 (32.5)
TDF+3TC+NVP 21 (13.6) 15 (9.8)
Change of ART regimen or individual drug Yes 45 (29.2) 47 (30.7) 0.803
No 109 (70.8) 107 (69.5)
History of treatment interruption Yes 6 (3.9) 4 (2.6) 0.520
No 148 (96.1) 150 (97.4)
  1. CPT Cotrimoxazole Prophylaxis therapy, IPT Isonized Prophylaxis therapy, AZT Zidovudine, d4t Stavudine, TDF Tenofovir, 3TC Lamuvidine, NVP Nevirapine, EFV Efavirnez