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Table 2 Incidence rates of TB divided into three 6-year periods

From: Epidemiology and outcome of HIV patients in Finland co-infected with tuberculosis 1998–2015

  Events Person yearsa Incidence rate (95% CI) Score test for trend of rates P-value
Rate ratio (95% CI)
Total 0.41 (0.29–0.59) < 0.001
 1998–2003 22 0.0318 691.2 (455.1–1049.7)   
 2004–2009 20 0.0543 368.5 (237.7–571.1)   
 2010–2015 11 0.0847 129.9 (71.9–234.5)   
Sex
 Female 0.57 (0.31–1.04) 0.068
  1998–2003 6 0.0086 698.7 (313.9–1555.3)   
  2004–2009 6 0.0144 416.9 (187.3–928.0)   
  2010–2015 6 0.0241 248.8 (111.8–553.9)   
 Male 0.35 (0.23–0.54) < 0.001
  1998–2003 16 0.0232 688.4 (421.8–1123.7)   
  2004–2009 14 0.0399 351.0 (207.9–592.6)   
  2010–2015 5 0.0606 82.5 (34.4–198.3)   
Mode of transmission
 IDU 0.29 (0.14–0.60) < 0.001
  1998–2003 8 0.0068 1182.2 (591.2–2363.9)   
  2004–2009 3 0.0113 265.0 (85.5–821.6)   
  2010–2015 1 0.0114 88.0 (12.4–625.0)   
 MSM 0.19 (0.08–0.45) < 0.001
  1998–2003 6 0.0132 454.3 (204.1–1011.2)   
  2004–2009 3 0.0220 136.4 (44.0–423.0)   
  2010–2015 0 0.0345 0   
 Heterosex 0.35 (0.23–0.54) < 0.001
  1998–2003 8 0.0113 709.5 (354.8–1418.6)   
  2004–2009 13 0.0196 663.0 (385.0–1141.8)   
  2010–2015 9 0.0362 248.3 (129.2–477.3)   
Place of birth
 Finland 0.30 (0.18–0.49) < 0.001
  1998–2003 15 0.0264 567.2 (342.0–940.9)   
  2004–2009 7 0.0427 163.9 (78.1–343.7)   
  2010–2015 3 0.0593 50.6 (16.3–156.9)   
 Sub-Saharan Africa 0.27 (0.12–0.59) < 0.001
  1998–2003 5 0.0025 2017.2 (839.6–4846.4)   
  2004–2009 5 0.0047 1063.1 (442.5–2554.1)   
  2010–2015 2 0.0103 194.8 (48.7–778.9)   
 Other 0.50 (0.24–1.05) 0.066
  1998–2003 2 0.0024 829.0 (207.3–3314.7)   
  2004–2009 8 0.0063 1261.5 (630.9–2522.5)   
  2010–2015 5 0.0145 344.2 (143.3–826.9)   
  1. aTime at risk in years per 100,000 persons
  2. Here the incidence rates of TB cases in the HIV cohort are shown divided into three 6-year periods. Score test for trend of rates shows the change in incidence between the 6-year periods. Rate ratios and 95% confidence intervals are calculated with the Mantel-Haenszel method