Prevalence of and risk factor for community-onset third-generation cephalosporin-resistant Escherichia coli bacteremia at a medical center in Taiwan

Table 3 Disease severity and outcomes for patients by whether they received effective empirical antibiotic treatment

Disease severity / Outcomes	Community-onset bacteremia			Community-acquired bacteremia			Urosepsis
Disease severity / Outcomes	Effective Tx (n = 564)	Ineffective Tx (n = 112)	P value	Effective Tx (n = 267)	Ineffective Tx (n = 36)	P value	Effective Tx (n = 281)	Ineffective Tx (n = 54)	P value
Charlson comorbidity index, median (range)	2 (0–11)	2 (0–13)	0.587^b	1 (0–10)	1 (0–6)	0.294^b	2 (0–11)	2 (0–11)	0.413^b
Shock upon presentation (%)	94 (16.7)	13 (11.6)	0.180	19 (7.1)	1 (2.8)	0.487^c	35 (12.5)	3 (5.6)	0.166^c
Death within 14 days (%)	54 (9.6)	10 (8.9)	0.831	6(2.3)	0(0)	0.364	13(4.6)	2(3.7)	0.764
Hospital stay, median days (range)^a	14 (3–159)	17 (6–80)	0.005^b	12 (3–44)	16 (6–52)	0.002^b	14 (3–159)	15 (7–80)	0.039^b

^aExcluding patients who died during hospitalization (Among patients with community-onset bacteremia, only 413 patients who received effective empirical antibiotic treatment and 83 patients who received ineffective empirical antibiotic treatment were analyzed. In community-acquired bacteremia group, only 191 patients who received effective empirical antibiotic treatment and 28 patients who received ineffective empirical antibiotic treatment were analyzed, whereas in urosepsis group, only 223 patients who received effective empirical antibiotics and 41 patients who received ineffective empirical antibiotic treatment were analyzed)
^bCompared by Mann–Whitney U test
^cCompared by Fisher’s exact test
Abbreviation: Tx empirical antibiotics treatment

ISSN: 1471-2334