Table 1 Clinical and demographic characteristics of EV-A71 and CV-A16 caused severe HFMD
Variable | EV-A71 (90) n (%) | CV-A16 (144) n (%) | χ2 | P |
|---|---|---|---|---|
Age | ||||
< 1 | 8 | 14 | 0.789 | 0.852 |
1–3 | 48 | 75 | ||
3–5 | 23 | 45 | ||
> 5 | 11 | 23 | ||
Gender (M) | 51(56.67) | 85(59.02) | 0.127 | 0.722 |
WBC (> 15 × 109/L) | 67(74.44) | 79(54.86) | 9.052 | 0.003 |
CRP (> 40 mg/L) | 59(65.56) | 86(59.72) | 0.800 | 0.371 |
BS (> 6 .8mmol/L) | 10(11.11) | 9(6.25) | 1.754 | 0.185 |
CKMB (> 25 IU/L) | 63(70) | 92(63.89) | 0.925 | 0.336 |
ALT (> 40 IU/L) | 9(10) | 9(6.25) | 1.097 | 0.295 |
WBC in CSF (> 40 × 106/L) | 10(11.11) | 1(0.69) | 13.415 | 0.000 |
Protein in CSF (> 450 mg/L) | 9(10) | 1(0.69) | 11.724 | 0.001 |
Fever | 81(90) | 119(82.63) | 2.417 | 0.12 |
Nausea | 3(3.33) | 2(1.39) | 1.001 | 0.317 |
Vomiting | 31(34.44) | 28(19.44) | 6.609 | 0.01 |
Myoclonic twitching | 19(21.11) | 11(7.64) | 8.994 | 0.003 |
Startle | 21(23.33) | 20(13.89) | 3.418 | 0.064 |
IVIG | 28(31.11) | 19(13.19) | 11.076 | 0.001 |