Skip to main content

Table 1 Clinical and demographic characteristics of EV-A71 and CV-A16 caused severe HFMD

From: Clinical characteristics and managements of severe hand, foot and mouth disease caused by enterovirus A71 and coxsackievirus A16 in Shanghai, China

Variable EV-A71 (90)
n (%)
CV-A16 (144)
n (%)
χ2 P
Age
  < 1 8 14 0.789 0.852
 1–3 48 75
 3–5 23 45
  > 5 11 23
Gender (M) 51(56.67) 85(59.02) 0.127 0.722
WBC (> 15 × 109/L) 67(74.44) 79(54.86) 9.052 0.003
CRP (> 40 mg/L) 59(65.56) 86(59.72) 0.800 0.371
BS (> 6 .8mmol/L) 10(11.11) 9(6.25) 1.754 0.185
CKMB (> 25 IU/L) 63(70) 92(63.89) 0.925 0.336
ALT (> 40 IU/L) 9(10) 9(6.25) 1.097 0.295
WBC in CSF (> 40 × 106/L) 10(11.11) 1(0.69) 13.415 0.000
Protein in CSF (> 450 mg/L) 9(10) 1(0.69) 11.724 0.001
Fever 81(90) 119(82.63) 2.417 0.12
Nausea 3(3.33) 2(1.39) 1.001 0.317
Vomiting 31(34.44) 28(19.44) 6.609 0.01
Myoclonic twitching 19(21.11) 11(7.64) 8.994 0.003
Startle 21(23.33) 20(13.89) 3.418 0.064
IVIG 28(31.11) 19(13.19) 11.076 0.001
  1. Abbreviations: WBC white blood cell, CRP C reactive protein, BS blood sugar, CKMB creatinekinase MB, ALT alanine aminotransferase, CSF cerebral spinal fluid, IVIG intravenous gamma globulin intervention
\