Variable | Univariable analysis | Multivariable analysis | ||
---|---|---|---|---|
Slope coefficient [95%CI] | p-value | Slope coefficient [95%CI] | p-value | |
Female | 0.6 [0.07;1.2] | 0.029 | 0.6 [0.05;1.2] | 0.034 |
Age (as a continuous variable) | − 0.02 [− 0.05;0.006] | 0.11 |  |  |
Level of education | ||||
 Informal | Ref |  |  |  |
 Any primary schooling | 0.2 [− 0.5;0.9] | 0.56 |  |  |
 Any secondary schooling | −0.08 [− 1.8;1.6] | 0.92 |  |  |
 Any university | 0.03 [− 0.98;1.04] | 0.95 |  |  |
Time on ART | ||||
 6 m-1y | Ref |  |  |  |
 1–2y | −1.6 [−4.0;0.8] | 0.20 |  |  |
 2–3y | −1.0 [− 3.4;1.4] | 0.40 |  |  |
 >3y | − 0.7 [− 3.0;1.6] | 0.53 |  |  |
History of change ART Regimen | 0.2 [− 0.4;0.8] | 0.42 |  |  |
Highest/Peak CD4 (cells/μL) | ||||
 < 200 | Ref |  |  |  |
 200–500 | −0.8 [− 1.6;-0.05] | 0.037 |  |  |
 500–1000 | − 1.1 [− 1.9;-0.3] | 0.011 |  |  |
 > 1000 | −3.0 [− 6.2;0.2] | 0.068 |  |  |
Current CD4 (cells/μL) | ||||
 < 100 | Ref |  | Ref |  |
 100–200 | − 0.5 [− 1.2;0.08] | 0.090 | −0.5 [− 1.1;0.2] | 0.15 |
 200–300 | −1.4 [−2.2;-0.7] | < 0.001 | -1.3 [− 2.1;-0.5] | 0.001 |
 > 300 | -2.8 [−5.0;-0.6] | 0.014 | -3.0 [− 5.2;-0.8] | 0.007 |
History of stopping ART | −0.05 [− 0.7;0.6] | 0.89 |  |  |
Use of herbal/alternative medicine | −0.1 [− 0.7;0.4] | 0.61 |  |  |
Other comorbidities | ||||
 None | Ref |  |  |  |
 Hypertension | −0.7 [− 1.9;0.6] | 0.30 |  |  |
 Others (Diabetes, heart failure, asthma etc.) | −0.7 [− 2.2;0.8] | 0.34 |  |  |
Anemia | 0.8 [0.3–1.4] | 0.005 |  |  |
Schistosome positivity | 0.15 [− 0.5;0.8] | 0.63 | 0.1 [−0.4;0.7] | 0.68 |
Ln of CAA (in ln pg/mL) | 0.03 [−0.04;0.1] | 0.42 |  |  |
Years infected with HIV-1 | 0.1 [0.01;0.2] | 0.027 | 0.06 [−0.06;0.2] | 0.32 |