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Table 3 Characteristics of individuals with B. pertussis PCR-positive results that were interviewed following the unusual increase in B. pertussis PCR detection rate in August 2014 (N = 17)

From: Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

Case Age group HIV status Confirmed/possible pertussis* Cough ≥2 weeks Paroxysmal cough Inspiratory whoop Posttussive vomiting Apnea Meets clinical case definition
1 < 1y Negative Possible No No No No No No
2 1-4y Positive Confirmed Yes Yes No No N/A Yes
3 25-44y Positive Confirmed No No No No No No
4 25-44y Negative Confirmed Yes Yes No No N/A Yes
5 25-44y Positive Possible Yes No No No N/A No
6 45-64y Negative Confirmed Yes No No No N/A No
7 45-64y Negative Possible Yes No No No N/A No
8 45-64y Positive Possible Yes Yes Yes No N/A Yes
9 1y Negative Confirmed Yes Yes No No Yes Yes
10 25-44y Positive Confirmed Yes Yes Yes No N/A Yes
11 < 1y Unknown Confirmed Yes Yes Yes Yes Yes Yes
12 1-4y Unknown Possible Yes No No No N/A No
13 1-4yy Positive Possible Yes No No Yes N/A Yes
14 5-14y Unknown Possible Yes Yes No No N/A Yes
15 25-44y Negative Possible Yes No No Yes N/A Yes
16 25-44y Negative Confirmed Yes Yes Yes No N/A Yes
17 5-14y Unknown Confirmed Yes Yes Yes Yes N/A Yes
  1. y = age in years. *Confirmed case = positive for B. pertussis with IS481 Ct < 35; Possible case = positive for B. pertussis with IS481 35 ≥ Ct ≤ 39. Clinical case definition = cough > 2 weeks (any duration in infants <1 year) + one of the following: paroxysmal cough, inspiratory whoop, posttussive vomiting, apnea in infants < 1 year