Table 5 Prognostic factors associated with the development of sepsis and septic shock in PLA patients
Variable (N = 332) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
Yes N = 154 | No N = 178 | P value | OR (95% CI) | P value | |
Age (years; median, range) | 56(18–85) | 59(20–89) | 0.290 | ||
Gender (Male/Female) | 88/66 | 99/79 | 0.780 | ||
Etiologies (n, %) | |||||
Biliary source | 53(34.1%) | 54(30.3%) | 0.428 | ||
Portal vein seeding, bowel and/or pelvic pathology | 17(11.0%) | 12(6.7%) | 0.167 | ||
Hepatic artery seeding | 17(11.0%) | 2(1.1%) | < 0.001 | 0.105(0.023–0.486) | 0.004 |
Direct extension | 17(11.0%) | 22(12.4%) | 0.709 | ||
Trauma to the liver | 5(3.2%) | 7(3.9%) | 0.738 | ||
Cryptogenic infection | 45(29.2%) | 81(45.5%) | 0.002 | 1.406(0.824–2.397) | 0.211 |
Comorbidities (n, %) | |||||
Smoking | 49(31.8%) | 41(23.0%) | 0.073 | ||
Drinking | 33(21.4%) | 23(12.9%) | 0.039 | 0.617(0.329–1.154) | 0.131 |
Hypertension | 28(18.2%) | 41(23.0%) | 0.277 | ||
Diabetes mellitus | 56(36.4%) | 50(28.1%) | 0.107 | ||
Hepatobiliary malignant diseases | 20(13.0%) | 20(11.2%) | 0.625 | ||
Cholelithiasis | 58(37.7%) | 65(36.5%) | 0.829 | ||
Cirrhosis | 4(2.6%) | 10(5.6%) | 0.170 | ||
Viral hepatitis | 8(5.2%) | 15(8.4%) | 0.886 | ||
Coronary artery disease | 5(3.2%) | 10(5.6%) | 0.413 | ||
Surgery history | |||||
Abdominal surgery history | 81(52.6%) | 74(41.6%) | 0.045 | 0.617(0.368–1.035) | 0.067 |
Hepatobiliary surgery | 67(43.5%) | 62(34.8%) | 0.106 | ||
Other surgery | 14(9.1%) | 12(6.7%) | 0.427 | ||