Fig. 1From: Herd immunity alters the conditions for performing dose schedule comparisons: an individual-based model of pneumococcal carriagePCV13 Trial Simulated in Naïve Population. a VT carriage prevalence in all four trial arms (mean ± s.d.). Lines represent average VT prevalence across 50 simulations while shading is bounded by one standard deviation. b The difference in VT prevalence between the 3 + 1 and 2 + 1 trial arms (averaged across 50 simulations) graphed over time. c The difference in VT prevalence between the 3 + 1 and 1 + 1 trial arms (averaged across 10 simulations) graphed over time. The zero difference line is shown in redBack to article page