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Table 1 Clinical classification of cases based on to single and paired serum sample algorithm

From: Usefulness of paired samples for the Serodiagnosis of toxoplasmosis infection in a tertiary teaching Hospital in Malaysia

Study Group

n

Single Serum Sample, n (%)

Paired Serum Sample, n (%)

Acute

Chronic

Early

Acute

Reactivation

Recent

Possible congenital infection

Passive immunity from mother

Latent

Clinical Classification based on Serological Findings

 Pregnant Women

82

7 (8.5)

75 (91.5)

2 (2.4)

13 (15.8)

5 (6.1)

62 (75.6)

 Newborn and Infant

141

3 (2.1)

138 (97.9)

3 (2.1)

6 (4.3)

132 (93.6)

 Child > 1 years old

8

8 (100)

2 (25.0)

6 (75.0)

 Immunocompromised

66

2 (3.0)

64 (97.0)

2 (3.0)

29 (43.9)

35 (53.0)

 Ocular Toxoplasmosis

50

2 (4.0)

48 (96.0)

2 (4.0)

1 (2.0)

16 (32.0)

1 (2.0)

30 (60.0)

 Mother

135

2 (1.5)

133 (98.5)

1 (0.7)

1 (0.7)

5 (3.7)

1 (0.7)

127 (94.1)

 Suggestive of active cases

482

Yes

No

Yes

Yes

Yes

Yes

Yes

No

No

16 (3.3)

466 (96.7)

90 (18.7)

392 (81.3)

Treatment Initiation based on Serological and Clinical Findings

 Pregnant Women

82

2/7

1/75

2/2

2/13

0/5

0/62

 Newborn and Infant

141

3/3

0/138

3/3

0/6

0/132

 Child > 1 years old

8

1/8

1/2

0/6

 Immunocompromised

66

2/2

29/64

2/2

29/29

2/35

 Immunocompetent

185

3/4

16/181

3/3

2/2

11/21

1/2

3/157

 Ocular

50

2/2

16/48

2/2

1/1

11/16

1/1

3/30

 Mother

135

1/2

0/133

1/1

1/1

0/5

0/1

0/127

 Treatment initiation based on serology and clinical findings

482

10 (2.1)

47 (9.8)

56 (11.6)

5 (1.0)