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Table 5 Antimicrobial therapy in acute pancreatitis

From: The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance

Classification Duration of antimicrobial therapy Recommendation
Mild No antibiotics (grade 2A) No antibiotics (grade 2A)
Severe Up to 14 d (grade 3B) -Empiric therapy: CAR (IPM or MEM) (grade 3B)
-CAR sparing regimen: TZP or FQ (if proven antibiotic susceptibility of the recovered organisms) (grade 3B)
Infected pancreatic necrosis
  1. KEY: CAR carbapenems, d days, FQ fluoroquinolone, IPM imipenem, MEM meropenem, TZP piperacillin/tazobactam