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Table 1 Vaccine effectiveness against RVGE hospitalization during the post-vaccine period by age group

From: Effects of the rotavirus vaccine program across age groups in the United States: analysis of national claims data, 2001–2016

Age Group

Direct VE, % (95% CI)

Indirect VE, %

(95% CI)

Overall VE, %

(95% CI)

Total VE, %

(95% CI)

< 1

80* (70, 87)

79* (66, 87)

88* (82, 92)

96* (93, 97)

1

92* (87, 95)

59* (33, 76)

79* (65, 88)

97* (95, 98)

2

87* (76, 93)

43* (4, 67)

68* (44, 83)

93* (86, 96)

3

96* (89, 99)

42 (− 2, 68)

71* (47, 84)

97* (93, 99)

4

81* (53, 93)

36 (− 25, 68)

59* (22, 79)

88* (70, 96)

0–4

87* (83, 90)

60* (48, 69)

78* (71, 83)

95* (93, 96)

5–9

47 (− 12, 79)

48* (30, 61)

50* (34, 63)

72* (42, 89)

10–14

 

46* (14, 67)

Equivalent to indirect VEa

 

15–24

 

42* (10, 62)

 

25–44

 

56* (36, 70)

 

45–64

 

35* (9, 53)

 

All ages

  

69* (62, 76)

 
  1. *Represents significance at the alpha = 0.05 level
  2. aIndirect and overall VE are equivalent for children, adolescents, and adults over 9 years of age because there are no vaccinated individuals in these age groups