|
Studies included
|
Country
|
Mycoplasma pneumonia patients
|
Control group
|
Mycoplasma pneumonia patients included in the staging
|
Detection method
|
Company of the reagent source
|
Gold standard
|
Blind
|
Value of the positive judgment
|
Results
|
FN
|
|---|
|
TP
|
FP
|
TN
|
|---|
|
Ryoichi Saito, 2005
|
Japan
|
6
|
89
|
No
|
LAMP
|
1.Roche Diagnostics
|
Real-time PCR
|
yes
|
2 × 10 2
|
6
|
0
|
89
|
0
|
|
2.Qiagen
|
|
3.Applied Biosystems
|
|
FEI ZHAO, 2013
|
China
|
21
|
59
|
No
|
LAMP
|
Qiagen
|
Real-time PCR
|
yes
|
unclear
|
21
|
5
|
54
|
0
|
|
Amy E. Ratliff II, 2014
|
American
|
22
|
192
|
No
|
LAMP
|
1.Qiagen
|
Real-time PCR
|
yes
|
C T ≤ 42.0
|
22
|
2
|
190
|
0
|
|
2.Agilent
|
|
Brianna L. Petrone, 2015
|
American
|
226
|
26
|
No
|
LAMP
|
1.Roche Applied Science
|
Real-time PCR
|
yes
|
CT < 30
|
200
|
1
|
25
|
26
|
|
2.Thermo Scientific
|
|
3.MP Biomedicals
|
|
Brianna L. Petrone, 2015
|
American
|
39
|
33
|
No
|
LAMP
|
1.Roche Applied Science
|
Real-time PCR
|
yes
|
CT ≥ 30
|
32
|
0
|
33
|
7
|
|
2.Thermo Scientific
|
|
3.MP Biomedicals
|
|
Fujio Kakuya, 2017
|
Japan
|
58
|
43
|
NO
|
LAMP
|
1.Eiken Chemical
|
Real-time PCR
|
Yes
|
an MP DNA load of> = 4.5 copies/μL
|
15
|
0
|
43
|
0
|
|
2.Asahi Kasei Pharma
|
|
Fujio Kakuya, 2017
|
Japan
|
58
|
50
|
NO
|
LAMP
|
1.Eiken Chemical
|
Real-time PCR
|
Yes
|
an MP DNA load of> = 4.5 copies/μL
|
8
|
0
|
43
|
7
|
|
2.Asahi Kasei Pharma
|
|
Ho Namkoong, 2018
|
Japan
|
73
|
84
|
No
|
LAMP
|
1. Mizuho Medy
|
Real-time PCR
|
yes
|
unclear
|
70
|
1
|
83
|
3
|
|
1. Fujifilm
|
|
2. Asahi Kasei Pharma
|
|
Xin Yuan, 2018
|
China
|
116
|
9
|
No
|
LAMP
|
1. Oxoid
|
Real-time PCR
|
yes
|
unclear
|
37
|
6
|
3
|
79
|
|
2. New England Biolabs
|
|
3. Da An Gene Co,
|
|
4. Sinopharm Chemical Reagents
|
|
5. Shanghai Simco Biotech
|
|
6. Beijing Mylab Corporation
|
- TP true positive, FP false positive, FN false negative, TN true negative
