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Table 1 Characteristics of the included studies

From: Diagnosis of mycoplasma pneumoniae by loop-mediated isothermal amplification: systematic review and meta-analysis

Studies included Country Mycoplasma pneumonia patients Control group Mycoplasma pneumonia patients included in the staging Detection method Company of the reagent source Gold standard Blind Value of the positive judgment Results FN
TP FP TN
Ryoichi Saito, 2005 Japan 6 89 No LAMP 1.Roche Diagnostics Real-time PCR yes 2 × 10 2 6 0 89 0
2.Qiagen
3.Applied Biosystems
FEI ZHAO, 2013 China 21 59 No LAMP Qiagen Real-time PCR yes unclear 21 5 54 0
Amy E. Ratliff II, 2014 American 22 192 No LAMP 1.Qiagen Real-time PCR yes C T ≤ 42.0 22 2 190 0
2.Agilent
Brianna L. Petrone, 2015 American 226 26 No LAMP 1.Roche Applied Science Real-time PCR yes CT < 30 200 1 25 26
2.Thermo Scientific
3.MP Biomedicals
Brianna L. Petrone, 2015 American 39 33 No LAMP 1.Roche Applied Science Real-time PCR yes CT ≥ 30 32 0 33 7
2.Thermo Scientific
3.MP Biomedicals
Fujio Kakuya, 2017 Japan 58 43 NO LAMP 1.Eiken Chemical Real-time PCR Yes an MP DNA load of> = 4.5 copies/μL 15 0 43 0
2.Asahi Kasei Pharma
Fujio Kakuya, 2017 Japan 58 50 NO LAMP 1.Eiken Chemical Real-time PCR Yes an MP DNA load of> = 4.5 copies/μL 8 0 43 7
2.Asahi Kasei Pharma
Ho Namkoong, 2018 Japan 73 84 No LAMP 1. Mizuho Medy Real-time PCR yes unclear 70 1 83 3
1. Fujifilm
2. Asahi Kasei Pharma
Xin Yuan, 2018 China 116 9 No LAMP 1. Oxoid Real-time PCR yes unclear 37 6 3 79
2. New England Biolabs
3. Da An Gene Co,
4. Sinopharm Chemical Reagents
5. Shanghai Simco Biotech
6. Beijing Mylab Corporation
  1. TP true positive, FP false positive, FN false negative, TN true negative