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Table 2 Antimicrobial susceptibility of S. pneumoniae isolated from children with AOM

From: Etiology of acute otitis media and phenotypic-molecular characterization of Streptococcus pneumoniae isolated from children in Liuzhou, China

Antibiotic Susceptible n (%) Intermediate n (%) Resistant n(%) MIC50 (μg/mL) MIC90 (μg/mL)
Penicillin Parenterala 36 (97.3) 1 (2.7) 0 (0.0) 0.15 1
Penicillin Oral 5 (13.5) 22 (59.5) 10 (27.0) 0.15 1
Vancomycin 37 (100.0) 0 (0.0) 0 (0.0) 0.5 0.5
Erythromycin 0 (0.0) 1 (2.7) 36 (97.3) 1 2
Levofloxacin 36 (97.3) 1 (2.7) 0 (0.0) 0.5 1
Tetracycline 1 (2.7) 0 (0.0) 36 (97.3) 4 16
Trimethoprim-sulfamethoxazole 6 (16.2) 3 (8.1) 28 (75.7) 0.5/0.95 0.5/0.95
Linezolid 37 (100.0) 0 (0.0) 0 (0.0) 0.5 0.5
Chloramphenicol 34 (91.9) 0 (0.0) 3 (8.1) 2 4
Cefotaximea 31 (83.8) 4 (10.8) 2 (5.4) 1 2
  1. AOM, acute otitis media
  2. a2016 CLSI breakpoints were considered for nonmeningitis