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Table 2 Distribution of signs meeting SIRS criteria in patients with sepsis or septic shock*

From: Systemic inflammatory response syndrome in Sepsis-3: a retrospective study

Variable All Patients (n = 631) Patients with SIRS-Positive Severe Sepsis (n = 538) Patients with SIRS-Negative Severe Sepsis (n = 93)
SIRS criterion met — no. (%)a
 Abnormal temperature 630 (99.8) 250 (46.5) 6 (6.5)
 Increased heart rate 631 (100) 506 (94.1) 43 (46.2)
 Increased respiratory rate or decreased PaCO2 630 (99.8) 448 (83.3) 15 (16.1)
 Abnormal white-cell count 629 (99.7) 331 (61.6) 13 (14.1)
No. of SIRS criteria met
 Median 3 3 1
 Interquartile range 2–3 2–3 1–1
 Distribution
  > 1 538 (85.3) 538 (85.3) 0
  0 16 (2.5)   16 (17.2)
  1 77 (12.2)   77 (82.8)
  2 200 (31.7) 200 (37.2) 0
  3 218 (34.5) 218 (40.5) 0
  4 120 (19.0) 120 (22.3) 0
  1. * P < 0.001 for all comparisons between the SIRS-positive group and the SIRS-negative group. PaCO2 denotes partial pressure of arterial carbon dioxide
  2. a SIRS criteria are defined in the Supplementary Appendix. Patients may have more than one criterion