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Table 2 Characteristics of patients with clinical cure and clinical failure

From: Procalcitonin, mid-regional proadrenomedullin and C-reactive protein in predicting treatment outcome in community-acquired febrile urinary tract infection

  Clinical cure (n = 229) Clinical failure (n = 20) P value
Age (years) 60 (45–73) 56 (46–71) 0.412
Male sex 94 (41) 7 (35) 0.597
Urologic history
 Indwelling urinary catheter 7 (3) 0 0.428
 Urinary tract disordera 71 (31) 4 (20) 0.304
 Recurrent UTIb 50 (22) 7 (35) 0.191
Comorbidity
 Diabetes mellitus 32 (14) 1 (5) 0.256
 Malignancy 16 (7) 1 (5) 0.735
 Heart failure 21 (9) 0 0.157
 Cerebrovascular disease 12 (5) 1 (5) 0.963
 Chronic renal insufficiency 8 (3) 1 (5) 0.729
 COPD 27 (11) 2 (10) 0.899
 Immunocompromised 14 (6) 1 (5) 0.841
Presentation
 At emergency department 160 (70) 15 (75) 0.630
 Antibiotic pre-treatment 71 (31) 2 (10) 0.048
 Fever duration, hours 36 (18–72) 48 (24–120) 0.279
 Dysuria 175/224 (78) 13/19 (68) 0.332
 Flank pain 142/225 (63) 17 (85) 0.049
 Suprapubic pain 116/222 (52) 11 (55) 0.814
 Perineal pain 11/222 (5) 0/19 (0) 0.321
 Systolic BP, mmHg 130 (116–146) 130 (115–150) 0.753
 Diastolic BP, mmHg 74 (63–85) 72 (68–83) 0.585
 Heart rate, beats/minute 93 (80–107) 96 (78–110) 0.695
Cultures
 Positive urine culture 158 (69) 13 (65) 0.712
 Escherichia coli 133/158 (84) 10/13 (77) 0.497
 Positive blood culture 42/220 (19) 3 (15) 0.654
 Positive urine and/or blood culture 169 (74) 14 (70) 0.712
Treatment
 Short antimicrobial treatment (7 days) 82 (36) 10 (50) 0.207
 Days of AB, mean (SD) 11 (3.3) 11 (3.5) 0.252
 Ciprofloxacin 208 (91) 18 (90) 0.902
 Amoxicillin (± clavulanic acid) 11 (5) 2 (10) 0.316
 TMP/SMX 5 (2) 0 0.504
 Otherc 5 (2) 0 0.504
 Initial intravenous dose(s) of AB 135 (59) 12 (60) 0.927
 Randomized 155 (68) 10 (50) 0.109
 Outpatient treatment 89 (39) 7 (35) 0.733
  1. Data presented as number (%) or median (IQR)
  2. BP blood pressure, AB antibiotics, TMP/SMX trimethoprim-sulfamethoxazole
  3. aany functional or anatomical abnormality of urinary tract except urinary catheter
  4. b≥3 UTIs in past 12 months or ≥ 2 UTIs in past 6 months
  5. ccefuroxime iv n = 2, meropenem iv n = 1, moxifloxacin n = 1, flucloxacillin n = 1