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Table 3 Clinical and Cognitive Outcomes of the Subset of Participants with Follow-up (n = 54)a

From: Cognitive screening in treatment-naïve HIV-infected individuals in Hong Kong – a single center study

 

Baseline

Follow-up

p-value

CD4+ T-lymphocyte (cells/μL)

248 (46–355)

468 (261–673)

< 0.001

On cART with CPE > 7, n (%)

7 (13)

HIV-1 RNA suppressionb, n (%)

46 (85)

IHDS score

10 (10–11)

11 (10–12)

< 0.001

IHDS ≤10, n (%)

31 (57)

17 (32)

< 0.001

MoCA score

27 (26–29)

27 (26–28)

0.818

MoCA ≤25, n (%)

13 (24)

12 (22)

1.000

MoCA ≤21, n (%)

4 (7)

4 (7)

1.000

  1. Median (IQR) is presented unless specified otherwise
  2. aOnly included participants who were on cART
  3. bBlood HIV-1 RNA level < 20 copies/mL
  4. Abbreviations: IHDS International HIV Dementia Scale, MoCA Montreal Cognitive Assessment, CPE CNS penetration-effectiveness