A superiority of viral load over CD4 cell count when predicting mortality in HIV patients on therapy

Table 2 Effects of changes in CD4 cell count levels on viral load transition intensities

	Baseline	Log-linear	Hazard	CD4Level
α _ij	\( {\alpha}_{ij}^0 \)	β _ij		k = 1	k = 2	k = 3	k = 4
α ₁₂	0.4679	0. 2451	1. 2778	0. 2685	0.3429	0.4380	0.5595
α ₁₆	0.0170	0.0732	1.0760	0.0144	0.0155	0.0167	0.0179
α ₂₁	3.1857	0.0612	1.0631	2.7644	2.9426	3.1325	3.3345
α ₂₃	5.6586	0.8919	2.4397	0.7877	1.8778	4.4768	10.6725
α ₂₆	0.1388	1.5639	4.7776	0.0044	0.0201	0.0921	0.4222
α ₃₂	30.4528	0.8684	2.3831	4.4659	10.4049	24. 2421	56.4807
α ₃₄	3.1488	−0.0002	0.9998	3.1766	3.1644	3.1521	3.1399
α ₃₆	0.0072	−0.1439	0.8660	0.0126	0.0099	0.0077	0.0060
α ₄₃	16.9641	0.5376	1.7119	5.0556	8.6181	14.6914	25.0443
α ₄₅	2. 2611	1. 2750	3.5789	0.1182	0.4339	1.5924	5.8438
α ₄₆	0.0096	−1.7277	0.1777	0.6964	0.1056	0.0160	0.0024
α ₅₄	6.5317	1.0211	2.7762	0.6131	1.7387	4.9311	13.9850
α ₅₆	0.0451	−2.5302	0.0796	23.7348	1.5009	0.0949	0.0060
-2xLL	2665. 285

α_ij:- transition intensities, \( {\alpha}_{ij}^0 \) baseline transition intensities, β_ij:- log-linear effects, Hazard:- hazard ratios, CD4Level:- CD4 cell count transient states, 2xLL:- likelihood ratio test