Types (No. of isolates) | Erythromycin MICs | Solithromycin MICs | Solithromycin MICs | P values | |||||
---|---|---|---|---|---|---|---|---|---|
(mg/L) | (mg/L) | (mg/L) | |||||||
Range | MIC50 | MIC90 | Range | MIC50 | MIC90 | ≤2 | ≥4 | ||
Total (236) | 1‐>256 | >256 | >256 | 0.0625‐>16 | 2 | >16 | 127 (53.8%) | 109 (46.2%) | <0.01 |
ermA (82) | 1‐>256 | >256 | >256 | 0.0625‐>16 | 1 | >16 | 65 (79.3%) | 17 (20.7%) | |
ermB (96) | 1‐>256 | >256 | >256 | 0.125‐>16 | 8 | >16 | 32 (33.3%) | 64 (66.7%) | |
ermC (58) | 1‐>256 | >256 | >256 | 0.125‐>16 | 2 | >16 | 30 (51.7%) | 28 (48.3%) | |
MSSA (88) | 1‐>256 | >256 | >256 | 0.0625‐>16 | 2 | >16 | 48 (54.6%) | 40 (45.4%) | 0.86 |
MRSA (148) | 1‐>256 | >256 | >256 | 0.0625‐>16 | 2 | >16 | 79 (53.4%) | 69 (46.6%) | |
iMLSB (66) | 1‐>256 | >256 | >256 | 0.0625‐>16 | 0.25 | >16 | 54 (81.8%) | 12 (18.2%) | <0.01 |
cMLSB (170) | 1‐>256 | >256 | >256 | 0.0625‐>16 | 4 | >16 | 73 (42.9%) | 97 (57.1%) | |
ERYS (30) | 1‐1 | 1 | 1 | 0.125–0.25 | 0.125 | 0.25 |