Severe fever with thrombocytopenia syndrome: comparison with scrub typhus and clinical diagnostic prediction

Table 5 Multivariate analysis for the predictive factors of SFTS compared to those of eschar-positive and negative scrub typhus

Variables	Odds ratio (95% CI)	P value
Age	1.03 (0.98–1.09)	0.145
Male gender	2.09 (0.58–7.44)	0.255
Diabetes mellitus	2.53 (0.36–17.43)	0.345
Hypertension	0.64 (0.12–3.28)	0.593
Duration, from onset of illness to initial visit	0.80 (0.68–0.94)	0.008
Altered mentality	2.31 (0.27–19.33)	0.439
Shock	1.72 (0.23–12.68)	0.592
Leukopenia (WBC < 4000/mm³)	30.13 (6.08–149.22)	< 0.001
Thrombocytopenia (< 80,000/mm³)	19.73 (4.60–84.58)	< 0.001
AST ≥400 IU/L	8.33 (0.39–176.07)	0.173
ALT ≥200 IU/L	0.36 (0.03–4.07)	0.411
LDH ≥800 IU/L	3.05 (0.65–14.15)	0.154
C-reactive protein < 1 mg/dL	67.46 (14.29–318.30)	< 0.001

Abbreviations: SFTS severe fever with thrombocytopenia syndrome, CI confidence interval, WBC white blood cell, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase