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Table 2 Clinical characteristics of patients with multidrug-resistant tuberculosis in association with pyrazinamide susceptibility

From: Underestimated pyrazinamide resistance may compromise outcomes of pyrazinamide containing regimens for treatment of drug susceptible and multi-drug-resistant tuberculosis in Tanzania

Characteristics All
N = 30
PZA (S)
N = 15
PZA(R)
N = 15
p-value
Mean age in years ±SD 33 ± 10 34 ± 8 31 ± 12 P = 0.44
Gender, Female (%N) 7 (23) 5 (33) 2 (13) P = 0.39
Smoking (%N) 6 (20) 3 (20) 3 (20) P > 0.99
HIV positive (%N) 6 (20) 5 (33) 1 (7) P = 0.17
On ART (%HIV positive) 5 (90) 4 (80) 1 (100) N/A
Prior TB treatment (%N) 25 (83) 13 (87) 12 (80) P = 0.63
Cavity on chest x-ray (%N) 8 (26.7) 5 (33.3) 3 (20) P = 0.68
  1. PZA pyrazinamide, S susceptible, R resistant, SD standard deviation, HIV human immunodeficiency virus, ART antiretroviral therapy, TB tuberculosis