From: APACHE-II score for anti-tuberculosis tolerance in critically ill patients: a retrospective study
Reason for drug withdrawal | n | % |
---|---|---|
Liver dysfunction | 71 | 42.5% |
Drug allergy | 25 | 15.0% |
Thrombocytopenia | 25 | 15.0% |
Disease deterioration | 12 | 7.2% |
Renal dysfunction | 10 | 6.0% |
Use of voriconazole | 7 | 4.2% |
Convulsions | 4 | 2.4% |
Gastrointestinal bleeding | 2 | 1.2% |
Economic reasons | 2 | 1.2% |
Based on resistance to the drug | 1 | 0.6% |
Malignant arrhythmia | 1 | 0.6% |
Psychiatric symptoms | 1 | 0.6% |
Unclear | 6 | 3.6% |
Total | 167 | 100.0% |