Fig. 3
From: Immune signatures for HIV-1 and HIV-2 induced CD4+T cell dysregulation in an Indian cohort
Expression of Granzyme B in CD4+T and CD8+T cells. a Comparison level of GrzB from CD4+ T and CD8+T cells among ART-naïve HIV-1(n = 14), HIV-2 (n = 13) infected individuals and seronegative individuals (n = 14). Statistical significance was evaluated by unpaired t test; *, p < 0.05; **, p < 0.01; and ***, p < 0.001. Gating strategy outlined in Additional file 4: Figure S4. b Correlation analysis between level of GrzB and frequency of Tregs cells in both ART-naïve HIV-1 (n = 10) and HIV-2 (n = 13) infected individuals.Spearman’s correlation test was used to determine the correlation coefficient (r) and the significance (p < 0.05)